Wwiizzkkiidd24

nice improvement being that he was a nw7 before.

I think the doc done well hear given the surface area he had to work with. and it's age appropriate. just out if curiosity what was the surface area? did the doc give you measurements..

Yeah I'd like to see more fue results myself. the one he just posted looks good and I look forward to seeing more of hes work.

nice improvement for the number of grafts used. well done doc

pictures?

well that's a nice result there for the patient. well done doc.

scar doesn't look to bad imo. hope all turns out well for you. happy growing.

nice result. well done doc.

should be interesting how they go about treating mpb with this drug but it could do more harm then good for pattern baldness simply because we have a better immune system then people who suffer from alopecia areata amd other sorts of alopecia. like you said it could open up a whole can of worms. I think the search continues for the cure of pattern baldness.

Inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth, a new study from researchers at Columbia University Medical Center has found. The research was published today in the online edition of*Science Advances. In experiments with mouse and human hair follicles, Angela M. Christiano, PhD, and colleagues found that drugs that inhibit the Janus kinase (JAK) family of enzymes promote rapid and robust hair growth when directly applied to the skin. The study raises the possibility that drugs known as JAK inhibitors could be used to restore hair growth in multiple forms of hair loss such as that induced by male pattern baldness, and additional types that occur when hair follicles are trapped in a resting state. Two JAK inhibitors have been approved by the U.S. Food and Drug Administration. One is approved for treatment of blood diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib). Both are being tested in clinical trials for the treatment of plaque psoriasis and alopecia areata, an autoimmune disease that causes hair loss. "What we've found is promising, though we haven't yet shown it is effective for male pattern baldness," said Dr. Christiano. "More work needs to be done to test formulations of JAK inhibitors specially made for the scalp to determine whether they can induce hair growth in humans." Christiano and her colleagues serendipitously discovered the effect of JAK inhibitors on hair follicles when they were studying a type of hair loss known as alopecia areata, caused by an autoimmune attack on the hair follicles. Christiano and colleagues reported last year that JAK inhibitors shut off the signal that provokes the autoimmune attack, and that oral forms of the drug restore hair growth in some people with the disorder. In the course those experiments, Dr. Christiano noticed that mice grew more hair when the drug was applied topically to the skin than when given internally. This suggested JAK inhibitors might have a direct effect on the hair follicles in addition to inhibiting the immune attack. When the researchers looked more closely at normal mouse hair follicles, they found that JAK inhibitors rapidly awakened resting follicles out of dormancy. Hair follicles do not produce hair constantly but rather by cycling between resting and growing phases. JAK inhibitors trigger the follicles' normal reawakening process, the researchers found. Mice treated for five days with one of two JAK inhibitors sprouted new hair within 10 days, greatly accelerating the hair follicle growth phase. No hair grew on untreated control mice in the same time period. "There are very few compounds that can push hair follicles into their growth cycle so quickly," said Dr. Christiano. "Some topical agents induce tufts of hair here and there after a few weeks, but very few have such a potent and rapid-acting effect." The drugs also produce longer hair from human hair follicles grown in culture and on skin grafted onto mice. It's likely that the drugs that are so effective in enhancing hair growth in the mice could affect the same pathways in human follicles, suggesting they could induce new hair growth and extend the growth of existing hairs in humans. It remains to be seen if JAK inhibitors can reawaken hair follicles that have been suspended in a resting state because of androgenetic alopecia (which causes male and female pattern baldness) or other forms of hair loss. So far, all the experiments have been conducted in normal mice and human follicles. Experiments to address hair follicles affected by hair loss disorders are under way. The title of the paper is: Pharmacologic inhibition of JAK-STAT signaling promotes hair growth. Other CUMC authors: Sivan Harel, Claire Higgins (now at Imperial College London) Jane E. Cerise, Zhenpeng Dai, James C. Chen, and Raphael Clynes (now at Bristol-Myers Squib). The work was supported in part by the NIH (grants R01AR056016, P30AR044535, T32GM082771 and T32GM007088), Locks of Love Foundation, Alopecia Areata Initiative, and the Dermatology Foundation (Career Development Award). copied and pasted from a website. That's much easier. ha.

I may have got that wrong ha it's to early in the morning

sounds really promising but it's my understanding that it's not for pattern baldness it's for people who suffer with(AA) androgenic areata. which is great because they deserve it much more then us pattern baldness sufferes.

Thanks for the advise mate I know what you're saying in regards to picking the right clinic there is one clinic which is not far from England who's work I really like and they way they go about things just in case something does happen God forbid so that's a box ticked and to be honest they click most of the boxes which is a plus. the only thing is there isn't much of there patients stories on here to get a gauge on but that isn't a bad thing and it's not to say there on another site like this I don't know I don't really venture out of this forum. I've had a few online consultations with some top docs recommended on this site and the general consensus is around 3-5k grafts. so I know pretty much what's needed it's just going about how to do it ie breaking them up into different surgery's to maximise the grafts survival or not. I definitely don't want a quick fix solution I'm okwith breaking the procedures up into 2 or 3 procedures if that means I'm going to get the best results. I do worry about going abroad but you only ever hear bout the bad stories and not the good ones where ever you go. it's just minimising the chance of the of bad story by like you said a clinic you feel comfortable with and ticks all the boxes. I know I've got a bit of hair on top but i could always do with some more haha.

I have to agree with the grafts estimate made by erdogan he's obviously compensating for future loss which will happen down the road. if you feel that is a bit OTT then go with on other surgeon thats more conservative.

Yeah CJD you need to back up your claims you've made with proof before you go pointing your finger.

hi there, it's a shame you had a bad experience with the doctor in question I also was under the impression he done most if not all of the procedure but that's not the case which is disappointing as you want the doctor to be heavily involved in every aspect of the procedure which he clearly is not. I did see a vidoe of hes on Youtube and he was doing all of the implanting with his techs loading up the the pen and he did say he's techs experience ranges from a couple months to ten years.I don't know if there still there or not but going by what you're saying theye can't be there anymore. I have seen some good results done by Dr hakan but only recently hastarted there been some average results posted by him or patients. I hope he fixes up otherwise I don't see how his recommendation can still stand. as for your picture agree with what has been said about your donor area it does look like shockloss thankfully it's still early and things can still turn around. be patient. I no its hard but just wait it out for a couple months I'm sure it will.get better.

nice work doc. looks really good.

if you're dead set on staying in England I'd suggest looking at farjo he's expensive but a good hair surgeon. other then that I'd look at going abroad where I get top quality doctors and for less the price. I'm from England also amd I've come to terms that it's best going abroad. unless money is no object to you then by all means stay in the country. hope this helps.

what a result that is. well done doc.

nice! you look very happy with the result.

I've always wondered how some clinics come up with these numbers of grafts did you over shoot or was the grafts lost. nice result none the less. well done.

what this guy said you done the hard part. now it's a waiting game. look forward to your updates.

is that including the strip? if you was to go down that route.

I believe it's normal mate not all grafts grow at the same rate weather it be left right centre or back of the head. I wouldn't of thought this would have a negative impact on the end result.

of course you can. it may be bit harder to get grafts out from those areas due to scaring but it's possible.