Topical Dutasteride

[mustang]

2 hours ago, Ronnieman said:

I am staying on 70mg TRT. No blasting for me that I forsee.

I'm gonna buy the LipoDut from Anagenica and see how that works.

My T is about 1400 ng/dl 

e2 I think is fine, a bit high but I don't mind

DHT I haven't got tested in a long time. 

No HCG or AI, It's just a standard TRT dose with no real sides 

Your lucky man

I am on HCG 150iu a day and can't tolerate even 35mg of T a week without the HCG to backfill the hormonal cascade. Just T gives me crazy anxiety and restlessness. 

It's either that or my Estrogen spikes up when adding both creating the anxiety, still trying to figure it out.

We will see. AI is a last resources, I am dropping body fat and started zinc/cialis/dim combo today.

My TT is 900 just on the HCG so have to add very little T to get to 1200, I don't want to go any higher as my BP is OK like this.

Funny thing, no hair loss on the HCG, not even shedding a hair a day.

[Ronnieman]

On 7/20/2021 at 11:02 AM, mustang said:

When on TRT CB0301 7.5%

Some people use oral 5 days a week and Topical twice a week 

Are you still on CB-03-01 mate? Did it work? I've heard conflicting reports which has stopped me from buying.

[mustang]

5 hours ago, Ronnieman said:

Are you still on CB-03-01 mate? Did it work? I've heard conflicting reports which has stopped me from buying.

CB works but I would suggest trying 1% EOD and see how you do.

[Melvin- Admin]

6 hours ago, Ronnieman said:

Are you still on CB-03-01 mate? Did it work? I've heard conflicting reports which has stopped me from buying.

Based on the clinical trials it’s similar to topical minoxidil. Finasteride or dutasteride would be better IMO.

[Ronnieman]

12 hours ago, Melvin- Moderator said:

Based on the clinical trials it’s similar to topical minoxidil. Finasteride or dutasteride would be better IMO.

This is just because I'm worried that I'll never be able to use Fin/Dut at a decent dose due to sexual sides. 

If this Lipo gel is legit for stopping sides for everyone, it will be a Godsend

[xhomer]

Anyone know how to ask pharmacy to formulate topical dutaste liposomde? Fueclinic has now the LipoDut what is the formula of this to as local pharmacy to compound?

[Melvin- Admin]

On 4/6/2023 at 12:10 AM, Ronnieman said:

This is just because I'm worried that I'll never be able to use Fin/Dut at a decent dose due to sexual sides. 

If this Lipo gel is legit for stopping sides for everyone, it will be a Godsend

It depends, I think liposomal topicals are the best. But it doe’s still go systemic, to a lower degree. The silicone base in the Xyon and farmacia parati make it even better IMO. It keeps it suspended and slow releasing on the scalp, which limits systemic absorption. But it does still absorb a little bit. 

[TRC79]

19 minutes ago, Melvin- Moderator said:

It depends, I think liposomal topicals are the best. But it doe’s still go systemic, to a lower degree. The silicone base in the Xyon and farmacia parati make it even better IMO. It keeps it suspended and slow releasing on the scalp, which limits systemic absorption. But it does still absorb a little bit. 

Have you followed up with blood test your self ? 

[Melvin- Admin]

3 minutes ago, TRC79 said:

Have you followed up with blood test your self ? 

No, I’m doing my follow up panel in July, when I hit 6 months. Once I have both, I will post them here.

[Mo1brag]

On 4/11/2023 at 7:02 PM, xhomer said:

Anyone know how to ask pharmacy to formulate topical dutaste liposomde? Fueclinic has now the LipoDut what is the formula of this to as local pharmacy to compound?

Hey man, I have been using the liposamal dutasteride from Dr. Knap at curemyhairloss.com. And honestly I think this is basically a cure. You can Ask him to formulate your own percentage of dut aswell. He is a doctor based in Denmark though so don’t know how temptikg that is for you if shipping costs Are high but this stuff works. 

[xhomer]

1 hour ago, Mo1brag said:

Hey man, I have been using the liposamal dutasteride from Dr. Knap at curemyhairloss.com. And honestly I think this is basically a cure. You can Ask him to formulate your own percentage of dut aswell. He is a doctor based in Denmark though so don’t know how temptikg that is for you if shipping costs Are high but this stuff works. 

how long have you been using? what is the price? how much you apply, concentration and when? everyday? and why you think is a cure?

Edited May 12, 2023 by xhomer

[Mo1brag]

2 hours ago, xhomer said:

how long have you been using? what is the price? how much you apply, concentration and when? everyday? and why you think is a cure?

I can only speak for myself of course, but because of the long half life I only apply 0.1% twice a week. For a couple of months ive been doing that and usually I use around 2ml per dosing. Ive been doing that paired with minoxidil and ketokonazole and im not losing hair. I should mind you I am 21 and extremely aggressive hair loss. I have seen other people do this regimen on Reddit without sht reduction systemically. Im not saying this works for everyone just my experience and there should be more study on it. It costs around 80 dollars.

Edited May 12, 2023 by Mo1brag
Spelling

[12345]

4 hours ago, Mo1brag said:

I can only speak for myself of course, but because of the long half life I only apply 0.1% twice a week. For a couple of months ive been doing that and usually I use around 2ml per dosing. Ive been doing that paired with minoxidil and ketokonazole and im not losing hair. I should mind you I am 21 and extremely aggressive hair loss. I have seen other people do this regimen on Reddit without sht reduction systemically. Im not saying this works for everyone just my experience and there should be more study on it. It costs around 80 dollars.

Did you have sides from oral or topical fin before trying dutasteride? 

How long have you been on the topical dut? Is 1 ml for a single application, and you are doubling it?

When you order it from curemyhairloss.com, how long will the order be processed and delivered to your home? i am located in the USA 

When you say aggressive hair loss, what Norwood are you? Is it just stopping hair loss, or is it helping to reverse miniaturization? 

[12345]

On 4/11/2023 at 1:36 PM, Melvin- Moderator said:

It depends, I think liposomal topicals are the best. But it doe’s still go systemic, to a lower degree. The silicone base in the Xyon and farmacia parati make it even better IMO. It keeps it suspended and slow releasing on the scalp, which limits systemic absorption. But it does still absorb a little bit. 

just for my own clarification, xyon has both the silicone base and the liposomal base? 

[Mo1brag]

29 minutes ago, 12345 said:

Did you have sides from oral or topical fin before trying dutasteride? 

How long have you been on the topical dut? Is 1 ml for a single application, and you are doubling it?

When you order it from curemyhairloss.com, how long will the order be processed and delivered to your home? i am located in the USA 

When you say aggressive hair loss, what Norwood are you? Is it just stopping hair loss, or is it helping to reverse miniaturization? 

Yes I had sides from finasteride. Lost some libido and very foggy brain. I have been using dutasteride topically for a few months. 1ml i single application and I am indeed doubling it so I can cover a bigger area. I dont know about delivery time to the US. Mine took around 1 month and I live in Norway. Regarding my hair loss you can look at my HTP thread, I was around a norwood 3-4 at 19. I got thicker and darker hair from finasteride and the dutasteride has made it better so I am probably losing a little hair but im not noticing any on the pillow/shower etc. Biggest thing for me is no sides, id rather lose a slight amount of hair than dealing with sides.

[12345]

31 minutes ago, Mo1brag said:

Yes I had sides from finasteride. Lost some libido and very foggy brain. I have been using dutasteride topically for a few months. 1ml i single application and I am indeed doubling it so I can cover a bigger area. I dont know about delivery time to the US. Mine took around 1 month and I live in Norway. Regarding my hair loss you can look at my HTP thread, I was around a norwood 3-4 at 19. I got thicker and darker hair from finasteride and the dutasteride has made it better so I am probably losing a little hair but im not noticing any on the pillow/shower etc. Biggest thing for me is no sides, id rather lose a slight amount of hair than dealing with sides.

Thanks for your thoughtful response.

Is there a recommended strength to begin with? I have seen different strengths available. from 0.5% to 2%. How do you know which strength to start at?

Is the liposomal formula, something that any compounding pharmacy can create? I have only seen it available in Europe and Canada (Xyon brand).  Do you think brand/pharmacy matters? 

And you use it 1 time a week?

Because you don't have sides, do you think it really goes less systemic bc of the larger  Dalton size?

 

Edited May 13, 2023 by 12345

[Mo1brag]

1 minute ago, 12345 said:

Thanks for your thoughtful response.

Is there a recommended strength to begin with? Is the liposomal formula, something that any compounding pharmacy can create? I have only seen it available in Europe and Canada (Xyon brand).  Do you think brand/pharmacy matters? 

 

I have seen different strengths available. from 0.5% to 2%. How do you know which strength to start at?

And you use it 1 time a week. 

Because you don't have sides, do you think it really goes less systemic bc of the larger  Dalton size?

 

No problem . I don’t think there is a recomended dose but in my opinion there is no need for anything higher than 0.5%. Dutasteride is so so potent and Even a slight increase could cause side effects. If I were you I would Get the 0.1% but it’s your choice of course. I would try getting it from Europe if you can’t find anything reputable in the US, I don’t know much about the US ones unfortunately. It really does matter how it is made because some formulations will give sides. The dalton weight matters but absorbtion can be slowed down according to vehicle for example liposamal vs just a watery liquid mix. This is all speculative im just saying what I’ve researched

[12345]

11 minutes ago, Mo1brag said:

No problem . I don’t think there is a recomended dose but in my opinion there is no need for anything higher than 0.5%. Dutasteride is so so potent and Even a slight increase could cause side effects. If I were you I would Get the 0.1% but it’s your choice of course. I would try getting it from Europe if you can’t find anything reputable in the US, I don’t know much about the US ones unfortunately. It really does matter how it is made because some formulations will give sides. The dalton weight matters but absorbtion can be slowed down according to vehicle for example liposamal vs just a watery liquid mix. This is all speculative im just saying what I’ve researched

On Monday I will call around some of the compounding pharmacies here to  to see if anyone local can make the liposomal formula.

What are your thoughts on. the xyon topical dut that's a 2%. It is supposed to have the silicon technology to slow the absorption, but its at the higher end of 2%. I know everything is all experiment  as in you have to try it, to see if you have sides from it, but in your experience do you think 2% is too much?

 

[mustang]

11 hours ago, 12345 said:

Thanks for your thoughtful response.

Is there a recommended strength to begin with? I have seen different strengths available. from 0.5% to 2%. How do you know which strength to start at?

Is the liposomal formula, something that any compounding pharmacy can create? I have only seen it available in Europe and Canada (Xyon brand).  Do you think brand/pharmacy matters? 

And you use it 1 time a week?

Because you don't have sides, do you think it really goes less systemic bc of the larger  Dalton size?

 

I would start with 0.025% (max 0.05%) once a week, 2ml for 3 months.

If your shedding stop or your hair looks the better and you have no side effects there is no reason to change anything.

I completely reversed hair loss with just once every 10 days. No sides.

 

[mustang]

21 hours ago, Mo1brag said:

Hey man, I have been using the liposamal dutasteride from Dr. Knap at curemyhairloss.com. And honestly I think this is basically a cure. You can Ask him to formulate your own percentage of dut aswell. He is a doctor based in Denmark though so don’t know how temptikg that is for you if shipping costs Are high but this stuff works. 

I just read his website and I am shocked with the amount of misinformation and conceptual mistakes. 

Not saying the products he prescribed aren't any good, they probably are but what a read. I can't believe a dermatologist would post such things.

[Mo1brag]

1 minute ago, mustang said:

I just read his website and I am shocked with the amount of misinformation and conceptual mistakes. 

Not saying the products he prescribed aren't any good, they probably are but what a read. I can't believe a dermatologist would post such things.

Like what? I haven’t gone in to depth reading his webside really I just saw people had great results with him.

[JP28]

On 4/4/2023 at 9:04 AM, mustang said:

Your lucky man

I am on HCG 150iu a day and can't tolerate even 35mg of T a week without the HCG to backfill the hormonal cascade. Just T gives me crazy anxiety and restlessness. 

It's either that or my Estrogen spikes up when adding both creating the anxiety, still trying to figure it out.

We will see. AI is a last resources, I am dropping body fat and started zinc/cialis/dim combo today.

My TT is 900 just on the HCG so have to add very little T to get to 1200, I don't want to go any higher as my BP is OK like this.

Funny thing, no hair loss on the HCG, not even shedding a hair a day.

Mustang what’s your take on the whole debate about creatine causing hairloss by increasing dht? 

[mustang]

19 minutes ago, JP28 said:

Mustang what’s your take on the whole debate about creatine causing hairloss by increasing dht? 

Tough one. Only one study and very limited data. 

Did it increase DHT? Yes. But it was also temporary if I recall correctly.

I wouldn't hesitate to take creatine if on Fin or Saw Palmetto or some form of 5AR blocker.

[12345]

3 hours ago, mustang said:

I would start with 0.025% (max 0.05%) once a week, 2ml for 3 months.

If your shedding stop or your hair looks the better and you have no side effects there is no reason to change anything.

I completely reversed hair loss with just once every 10 days. No sides.

 

hi mustang, just for clarification,  you are referring to the  0.025% liposomal dut?

[mustang]

Liposomal or Trichosol, it doesn't matter.

One might be more effective at delivering the drug and therefor less concentration can be used but both will work.