Follicle1984

Hi Can you update us about your results with regenera activa? I am considering it as I have few options. Anyone else had this and able to comment? Thanks

Hi Melvin, I don't think I'd be free to join the call but I'd be happy to list afew questions you could consider asking. Happy to private message them to you if you like.

Can I ask you Arthursam...how long before you noticed a reduced shed on cosmerna?

Well on a positive note that poster on reddit says he was actually happy with the product and it seems to have halted his hairloss. Obviously being underdosed is not good...but other than that. It does seem I'm reading some good things in various places about cosmerna and that it is stopping shedding in some people. Which is perhaps all we could ask for in these early months. I've now started to use it. Second application in. Nothing to note yet. Shedding appears the same. I'm using afew other things though too. But this is the new player, so I think any changes will largely be attributable to this.

Why thank you 😊 I try my best. Well I've come across one or two people who are more intelligent than myself with regards to metabolic chemistry...and there are some interesting hypotheses withbregards to how there may be alot of other things at play and interlinking with the androgen paradox. When I stopped to think about it all, I realised perhaps my finasteride side effects may relate to my overall health more than i cared at first to beleive. I think the issue is aswell with insulin resistance is that it can be hard to diagnose. Needing fasting insulin levels and not simply fasting sugars. And if this is out of whack it could cause a whole host of issues. I'm on a mission to clean up my metabolic chemistry at the moment.

That interesting. I've begun to wonder if finasteride and 5AR sexual side effects may possibly be related to insulin resistance, metabolic syndrome and endothelial dysfunction. Some evidence that dutasteride mesotherapy is less effective in insulin resistance also.

Thanks for sharing. Not discrediting your experience...but do you think there is a chance this may have been nocebo? After all, the mechanism this works by, causing reduction of the AR, should take a little time to come into play and equally take some time to rectify and rebuild levels of AR. If the symptoms came quickly and left quickly, it does make wonder if this MAY have been unrelated. The mind is a powerful thing after all.

Anyone with any updates on cosmerna?

It's a tricky one isn't it. I recently had some ED with alfatradiol too. I was reading into it. Turns out although 17alpha E2 is a weak estrogen in many tissues it can apparently act as a stronger estrogen in some other tissues...one being the brain. Which actually makes sense with me. Just have to find out what works for each of us i guess.

Ah OK. Thanks for clarification. Good you are working with a urologist I guess then. I'm glad cosme seems not to be giving you sides. The study from dermatest supposedly showed better results with twice weekly anyway so maybe no better than weekly. I think pairing it with an androgen receptor antagonist seems a good idea.

But no Erectile dysfunction on cosme?

Hi Arthur Sam. Can I ask do you apply cosmerna every week or every 2 weeks? Also...thanks for sharing your encouraging story. I too had awful sides from fin (both oral and topical) which has made me very nervous to even try topical dut. I figure I may give cosme a go...afew people stating its stopped their shedding. I'm shedding badly at the moment. So would be nice to have something to at least stabilise my loss. I presume still no side effects with cosme? Thanks

How you getting on with cosmerna?

I think I agree with you. As much as I agree with Melvin that any company faking before and after photos is not on (if that's what's happened here). That being said, It could be a disconnect... poor marketing decisions vs the science. Hopefully, the product at least may halt hairloss and prove an alternative to fin and dut. If it does this without sides, I'm taking that as a positive. As you say...we will know soon. Arthur Sam's testimonial is encouraging.

Anyone any further updates with their Cosmerna usage/results/sides?