HARIRI

HT India, you are looking great. I wish Dr. Bhatti will soon be recommended here. Congrats anyways for being recommended in the IAHRS as the first Asian FUE exclusive HT Doc. Pretty impressive. Dr, Bhatti and Dr. Hakan took Asia to a new level of HT reputation. I consider Antalya as an Asian city since its in the Asian side :-)

Looking great YAZ89. Keep it up, you went to one of my favorite FUE surgeons who I do really respect and appreciate. Dr. Erdogan uses latest technologies at no additional cost just to satisfy his patients, Indeed a real Turkish hospitality :-)

HW for sure, No comparison but if you want to save some money and get an affordable strip surgery. I advice you to check out Dr. Path in Thailand, Actually she was trained by him. Good luck.

Looking great Sevnblack. Your hair looking great. Keep us updated & looking forward for your 4th month photo :-)

Nice coverage, just another 3000 grafts and this man is totally restored. Thanks for the clear honest non flash pictures. Its amazing how Hairline can change the look of a person.

:eek: Mamma Mia :eek:

Hey Sevnblak, Any updates Buddy??? Its 3 months already ;-)

Here is a review I found in the internet between Viviscal and Nourkrin. From HairGrowthSOS Dot Com - Hope it helps:- Differences The main differences are in the mineral and vitamin composition, and there’s also a few extra ingredients that appear in one but not the other – for example, only Nourkrin contains fenugreek. Also, whilst both provide omega 3 essential fatty acids, Viviscal has flax seeds whereas Nourkrin has cod liver oil. Now here are the similarities... Similarities Both contain acerola (a fruit extract or powder providing vitamin C) and horsetail extract (at virtually the same dose in each of these products). Both contain marine-derived protein and at the same dose (Nourkrin has "Marilex" and Viviscal has "AminoMar C"). Both carry a warning of possible side effects: if you are allergic to the fish or shellfish ingredients from the marine protein, you should not take either product. A high price to pay? Both versions of this product are very expensive too! So, if you were thinking about using either of these products, it might be worth your while looking into cheaper alternatives - you should be able to get most of the ingredients from a combination of other supplements. And, whilst you would almost certainly have to take multiple products instead of just one, it might still be a better idea because, if they do help improve your hair growth, you'll need to take them long-term. Perhaps even for life. And clearly, if you were to choose either of the products reviewed on this page, eventually, that would accumulate into a small fortune! Still, on the other hand, some people might say that, if it saves your hair, it’s well worth it. Viviscal Ingredient AminoMar™ Marine Complex 452.9 mg † Vitamin C (from Acerola Powder and as Ascorbic Acid) 30 mg 50% Zinc (from Zinc Oxide) 8 mg 53% Flax Seed extract 50 mg † Horsetail (stem) extract 24.5 mg † ** Percent Daily Values are based on a 2,000 calorie diet. † Percent Daily Value not established Nourkrin Ingredient Marilex® Is the exclusive, proprietary ingredient in the tablets, and can only be found in the Nourkrin® products from Pharma Medico. Marilex® has been tried and tested all over the globe in connection with its registrations. Marilex® is recognised as completely safe and suitable for use in humans by all respective authorities including the FDA, as well as the European Food Safety Authority. Acerola cherry extract The special extract used in Nourkrin® is extremely rich in vitamin C, it also contains vitamins A, B1, B2 and B3 together with carotenoids and bioflavonoids which provide important nutritive value and antioxidant properties. The vitamin C produced by the carefully selected fruit is better absorbed by humans than other synthetic ascorbic acids. Fenugreek Through a meticulous process and approved technology, it is ensured that the Fenugreek used in the product has the exact profile required for the Nourkrin® MAN Hair Preservation Programme. Silica The silica used in Nourkrin® is of pharmaceutical grade and specially purified to meet the requirements of Pharma Medico. Horsetail extract This specially selected extract is rich in specific silica and silicic acids. The plant contains significant levels of the minerals potassium, manganese and selenium – as well as saponins and flavonoids. The special selection and extraction process ensures a well-balanced intake of the essential minerals. Cod liver oil extract The EPA and DHA levels in this special oil, together with the well-balanced vitamin A and D content, are made to the exact specifications required by Pharma Medico to be suitable for the Hair Preservation Programme. D-biotin Contributes to the maintenance of normal hair. In my own opinion I would go with Viviscal as its pretty similar with Nourkrin when it comes to ingredients. Nourkrin is freaking expensive and it doesnt worth this much money. Wish you all the luck Buddy :-)

Looking good but what is wrong with the video camera when the hair of the patient is being combed from minute 1:15 to 1:58? Its getting blurred somehow and the color turns to black!

Dr. Mwamba I cant imagine how great it will be to get a high class FUE session with the feature of Invitro Hair Doubling. If one day it becomes available at your clinic, you will be my number one choice to restore my crown. No doubt about that. Wish you all the best Doc.

In the hands of Lorenzo and Hakan, Implanter is much better than custom blades. It doesn't hurt the surrounding grafts plus leaves a very clean work with less blood. But keep in mind not every surgeon can use the implanter properly especially that the doctor handles all the recipient area work without any technician help while with custom blades he can create the slits and leave the implanting to the nurses which is somehow risky as well.

How wide was your scar before the scar revision? How many cm? :confused:

Mickey85, have you decided whether you will go for a FUE into scar or a scar revision? Its really been a while :)

Congratulation Buddy. You did the best decision and went to a great exclusive FUE surgeon with great knowledge in dealing with body hair. Dr. Hakan is one of my favorite BHT FUE surgeons along with Dr. Maras & Dr. Bisanga.

Its really great how Dr. Hakan managed to cover your crown which is considered the hardest spot as some call it (The Black Hole). How many grafts went into your crown out of the 4500 grafts?

Super clean and neat work Dr. Lorenzo. Every British hair loss sufferer is damn lucky for having the best FUE surgeon at his country. Keep it up amigo.

Good job but for the first time I see misleading pics from Dr. Koray Erdogan. Pre OP pics should never be with wet hair as it shows the person have less hair while he is not. I hope next time Pre op and Post op photos would be with dry hair and same combing style in order to be clear and transparent.

Good luck, If scar revision didn't meet your expectation you can always FUE some grafts into it from beard or chest if you want to save what remained in your donor.

I think CB-03-01 (Cortexolone 17alpha propionate) is the best topical Anti Androgen. Here some interesting points about CB-03-01 - an impressive reduction of sebacious gland size, observed in about 85% of treated subjects. - a decrease in dermal fibrosis, indicator of inflammatory process, after treatment mainly with CB-03-01 - a reduction of vessel diameter of peribulbar microvasculature - a reduction of inflammatory cells after treatment with CB-03-01 Here is also an interesting article with more information:- Cortexolone 17-alpha propionate (CB-03-01): Peripherally Selective Anti-Androgen Cortexolone 17-alpha propionate, also called CB-03-01, is a derivative of 11-deoxycortisone with peripheral, selective anti-androgen activity. Published data demonstrate that cortexolone 17α-propionate possesses therapeutic potential as a topical anti-androgen for skin disorders such as acne, as well as androgenic alopecia (male pattern baldness). Cortexolone boasts equal or greater safety and potentially greater efficacy compared to retinoids used to treat acne, as well as a more localized and therefore potentially safer and more effective mechanism as compared to systemic 5-alpha reductase drugs such as finasteride and dutasteride. Though not currently FDA-approved, if FDA approval is granted cortexolone 17-alpha propionate will be the first commercially available topical anti-androgen. Background and Timeline of Development According to the manufacturer, Italian company Cosmo Pharmaceuticals, cortexolone “tightly mimics the profile of an ideal anti-androgen for topical use”. The stated objective of the manufacturer is “to create a product for topical application to treat acne, male pattern baldness, and seborrhoea that does not have the side effects of products currently being taken in tablet form” which presumably would include oral isotretinoin (Accutane) and antibiotics for acne, and 5-AR inhibitors such as dutasteride (Avodart) and finasteride (Propecia) for male pattern baldness. Five clinical trials assessing the safety and efficacy of cortexolone 17-alpha propionate in European markets have been completed with favorable results, and non-clinical early data supporting the IND (investigational new drug) application was also deemed promising. Per US FDA code, each individual disease or disorder claimed to be treated by a drug will require separate applications for the drug approval process. According to Cosmo, an IND application for acne was granted by FDA in the first quarter of 2012, with phase II escalating dose trials in process at the time of this writing[1]. While the future appears bright for cortexolone 17-alpha propionate as an alopecia drug, the IND process has not been initiated at this time; the manufacturer has stated their intent to apply for an IND for androgenic alopecia in 2014. Anti-inflammatory and Anti-Androgenic Mechanism and Safety Profile and Rationale Due to a common androgenic pathway between inflammatory acne and androgenic alopecia, cortexolone 17-alpha propionate is considered a promising drug for both disorders. What is unique about cortexolone 17-alpha propionate is the peripheral and selective mechanism. Cortexolone has good penetrative properties, making it suitable for topical use, and while effective locally it is metabolized into a harmless, inactive parent compound prior to circulating systemically: “CB-03-01’s mechanism of action is based on the competitive activity between testosterone and DHT for androgen-receptors in the skin. CB-03-01 is devoid of systemic anti-androgenic activity, in as far as it does not inhibit gonadotropins hypersecretion, and has a moderate anti-inflammatory effect. In preclinical studies, CB-03-01 was shown to be rapidly metabolized by the skin to the parent compound cortexolone, which is a physiological steroid lacking anti-androgen activity and is completely safe. CB-03-01 has also been shown to have good penetration through the skin, making it the first anti-androgen suitable for topical application. The primary supporting study around which Cosmo bases their claims regarding safety and efficacy of topical anti-androgen therapy for acne was published in the British Journal of Dermatology in 2011. There are effective anti-androgens currently available, but they are not suitable for topical use and act in a systemic manner which, due to the pervasiveness of androgen activity and androgen receptors in physiological function throughout the body, results in a poor safety profile. As Cosmo CEO Mauro Ajani states, “drugs available for the treatment of acne are either not very effective or have substantial negative side effects”. The recent manufacturer-funded studies and internal data are abundant, but there is also early peer-reviewed data that is illustrative of the comparative potency, and safety rationale, of cortexolone (CB-03-01) compared to other drugs: “The aim of this study was to investigate the antiandrogenic activity of a new monoester of cortexolone, cortexolone 17alpha-propionate (CAS 19608-29-8, CB-03-01). Although the compound displayed a strong local antiandrogenic activity… it did not exhibit antiandrogenic activity in rats after subcutaneous injection, nor did it affect gonadotropins hypersecretion… As topical antiandrogen, the steroid resulted about 4 times more active than progesterone (CAS 57-83-0) and, when compared to known antiandrogen standards, it was about 3 times more potent than flutamide (CAS 13311-84-7), about 2 times more effective than finasteride …Its pharmacological activity seemed to be primarily related to its ability to antagonistically compete at androgen receptor level.” Comparative Efficacy Cortexolone 17-alpha propionate, Androgen Receptors, and AR-Targeted Treatment of Alopecia Compared to the recently-demonstrated PGD2 mechanism, knowledge of the effects of androgen receptor agonism is not cutting-edge; the mechanism was first mentioned in published literature in the late 1980s, and early off-label use of 5-alpha reductase (5AR) inhibitor drugs finasteride (then Proscar, now also Propecia) and Dutasteride (Avodart) existed in the 1990s prior to the approval of finasteride labeled for treatment of alopecia in 1997. 5AR inhibitors prevent the local enzymatic conversion of testosterone into dihydrotestosterone, which is 2.4-10 times more potent in its action at the androgen receptor than testosterone depending on tissue and action examined. However, they also reduce serum DHT levels, sometimes drastically, resulting in potentially undesirable effects. 5AR inhibitors are effective to prevent hair shedding when taken long-term by men with androgenic alopecia (AGA). However, lately there have been increasing concerns as to the short-term and long-term safety profiles of these drugs, both in civil courts and in the published literature: “Men who suffered ongoing erectile dysfunction after taking prescription drugs to treat prostate problems and male pattern baldness will be able to pursue a class-action lawsuit against the drug maker, a B.C. judge has ruled.” “The significant reduction in DFI within 3 months of finasteride cessation and continued improvement suggests a causal link between finasteride and sperm DNA damage. We hypothesize that low-dose finasteride may exert a negative influence on sperm DNA integrity, resulting in increased pregnancy losses. We suggest that in infertile men using finasteride, sperm DFI should be measured in addition to semen parameters, and a trial of discontinuation of finasteride may be warranted.” The likely primary mechanism of most or all reported side-effects not due to nocebo-type effect is systemic action of 5-alpha reductase. When taken orally, 5AR drugs have systemic action and are in no way confined in their action to the peripheral (local) area of effect, namely the scalps of balding men. Topical applications of finasteride preparations may reduce systemic circulation, but will not prevent this issue, since, unlike cortexolone, the finasteride gel that absorbs into the dermal layer can still be circulated systemically in its active form. The androgen-receptor-mediated mechanism is upstream of PGD2, meaning that it is hypothetically possible to reduce PGD2 levels to treat baldness without interfering with androgen levels. On the other hand, since PGD2 is likely associated in a general sense with inflammation, modulation of the androgen pathway may be an insufficient way to address baldness in some men if PGD2 elevation is caused by a pathway other than androgen receptor binding by DHT. Without more published PGD2 data, though, it is impossible to predict how future PGD2 inhibitor drugs may change the treatment landscape for AGA patients. It is reasonable to state that the androgen receptor pathway of baldness is well-demonstrated, well-studied, and is an effective target for drug development in the interest of treating androgenic alopecia. Cortexolone, with a distinct yet similar mechanism (competitive inhibition/receptor inactivation, preventing DHT-binding) is a major step forward in addressing the major downside to 5AR inhibition as a baldness treatment because, if approved, it may be as effective as systemic, orally-dosed 5AR inhibitors, and would almost certainly be safer.

Try to use Keratene Alphactive Retard. Its a credible DHT blocker without any sexual sides. Propecia is a libido killer. Stay away from it.

Check this out Guys:-

A brand new crown. Great coverage. Hail the king :D

By the way Doc, Congrats for the new pricing page in your website. Its very informative Good to know that Motorized and Manual FUE has the same rate at your clinic Pricing | AHD Clinic

By the way Doc, Congrats for the new pricing page in your website. Its very informative Good to know that Motorized and Manual FUE has the same rate at your clinic Pricing | AHD Clinic

If I just had enough cash, Dr. Lorenzo would be my first choice. No doubt about that! An extremely talented FUE surgeon. Golden fingers indeed :-)