Der3k7

16 minutes ago, 12345 said:

until there are non-biased studies, meaning studies not published by the manufacturer, in this case xyon, I honestly cant believe this to be true. its xyons selling point. i think sensitivities to meds is ultimately on an individual basis.

Do you think it is more likely that they are lying that their gel was specifically designed chemically to help prevent systemic absorption? And that other topical solutions have comparable amounts of systemic absorption rather than much more and it is just a marketing ploy?

I can get a skin fade with no issue

6 hours ago, 12345 said:

its interesting how you were not able to tolerate fin, but have been doing well in terms of being side effect free on topical dut. i tried topical dut once from anagenica and it shut me off  sexually for 6 weeks. 

Maybe it’s because xyon gel that dampens systemic absorption

Oh that’s good to know 

Anyone here use Nizoral shampoo active ingredient Ketoconazole? It’s supposed to help with hair loss too 

11 hours ago, arthurSam said:

Yes but problem is always the same : we don't know if pictures are real, and if guys have alopecia or just some deficiencies, if bald areas are old or not, ...

Have you seen positive results from your mesosome therapy yet 

There before and after in that video is pretty impressive though

Anyone know much about stem cell injections such as featured in this video? 
 

https://youtube.com/shorts/xFk2YO8Ca_Y?si=hhhaWzkWvlItiHho

11 minutes ago, Melvin- Admin said:

No, I blowdry my hair, then apply Xyon. 

And you don’t find that after doing all the parts and rubbing the gel onto the scalp that it causes your hair to be kind of unruly after? 

22 minutes ago, Mauricio said:

Dr Wong told you that their Topical Dutasteride is better than their Top Finasteride or that the Oral Dut is better than Oral Finasteride?

My question was phrased generally so the statement was that generally speaking dutasteride is more effective and said it’s perfectly fine for me to switch to xyon dutasteride instead of xyon finasteride 

1 minute ago, Melvin- Admin said:

I apply it at night as well. Right after my shower. I wake up, my hair doesn’t look messy at all. I think topical dut causes less sides because it penetrates slowly.

This is all speculation, but I think topical dut slowly reduces systemic DHT gradually. Your body probably doesn’t notice it. Because the drug molecule is large, it doesn’t penetrate right away like finasteride. This gives your body time to adjust, so you don’t experience side effects. I think side effects occur from the sudden drop in DHT. Just my speculation.

Do you apply it when your hair is still wet? I tend to wait for my hair to dry and because of all the parting and pushing the hair in different ways to get access to the scalp my hair usually looks kinda stupid after 

7 hours ago, Sunset Dune said:

 

I’ve been using Xyon Dutasteride everyday for nearly 5 months, I usually use more than 1 pump to get the gel all over the thinner areas of my scalp front and top. I just use my fingertip to spread it directly on different areas of the scalp. Doesn’t really look like there’s any difference to my crown yet, my front does look a lot thicker but that’s probably from the hair transplant. 
 

The topical gel makes hair look messy, it’s not the best look and isn’t as convenient as swallowing a pill so I might also consider switching to oral Finasteride (specifically brand name Propecia) if I don’t see any cosmetic difference. I’ll give it 18 months and then switch to oral Propecia.
 I personally wouldn’t recommend switching straight to oral dutasteride, try Finasteride (Propecia, not generic) first to see how you’ll tolerate the medicine if there actually are any side effects. Kevin Mann from hair cafe says dutasteride is actually inferior to Finasteride.

When I research the comparison it seems most articles say dutasteride is better and blocks more dht by more mechanisms. Also when I asked Dr wong which is better and he said dutasteride is better 

Considering I did have post finasteride syndrome and couldn’t get hard for my life for awhile after stopping oral finasteride it’s worth it for me to just use xyon dutasteride to protect myself even though it is a pain in the ass to apply and expensive 

Well it is a risk you take and accept when signing paperwork I believe. But would be nice to get reimbursement for waste of grafts 

2 hours ago, Sunset Dune said:

How?

I pump it all onto the bathroom sink then part my hair systematically from front to back left to right and dab it right onto the scalp between the parted sections and am able to spread it primarily in small sections all throughout and wong said it diffuses under the skin so it probably gets all throughout my scalp 

1 hour ago, Sunset Dune said:

Melvin, Have you ever tried using more than one pump to get full scalp coverage? On some days I use 3-5 pumps to get the gel on my entire scalp and I haven’t had any sides 

I’m able to spread one pump out throughout the entire scalp 

On 11/10/2023 at 4:43 PM, Melvin- Admin said:

It’s okay but probably overkill.

I’ve seen studies and articles saying they synergize and enhance benefit

I had a good result with wong and he’s one of the highest regarded as well. Do you think these other surgeons are better than wong? I thought about couto but I was hesitant because of lack of patient posted results on here

1 hour ago, consequence said:

The way to tell if your hair's improvement is the topical dut or not is to look at your systemic levels of DHT. I don't think the medication has much regional effect, it's mechanism is more likely systemic -- ie. oral minoxidil for me was much more effective than topical. But doing biopsies of your hair and immunofluorescent stains is probably not in your practical budget so until head to head studies come out this is all just inductive reasoning and podcast level broscience. 🫠

I think you should let your hair loss pattern stabilize with a consistent medical regimen for at least 1 year before considering another procedure, which it sounds like you're doing if you're waiting till Nov 2024. Otherwise you're filling a bucket of sand with a hole in the bottom.

Focusing on docs with a track record of patient submitted cases showing repairs similar to what you're looking for is also a good idea. Gabel, Cooley, Feriduni and Couto have had some superstar level revisions on the forums.

Also no more perms. 😇

Yeah no more perms yeah I’ll be on xyon and minoxidil most days. And yeah November next year will be 2 years after the last surgery with wong I plan to go to wing again it’s not really a revision or repair just need more grafts to reinforce some thin spots along hairline, corners, behind hairline, crown, and potentially some thinning strips in mid scalp. He said we can do 1000 grafts but I’m gonna see if maybe we can do 1250-1500 cuz honestly when I look at my head in the mirror it looks like I could benefit from more transfer of density from throughout the back of my scalp to reinforce the thinnest spots all throughout my head but we will see what he says when he sees me in person next November 

Oh I see, hmm

21 minutes ago, consequence said:

I'm not sure which studies @mxnprettynice was referring to but these are a few that popped up after a quick google:

• Minoxidil application study 1 
• Minoxidil application study 2
• Minoxidil application study 3
• Minoxidil with microneedling study

I think the idea is that once the minoxidil crystallizes its "thermodynamic activity" decreases. That being said, ethanol is also caustic and I'm not sure as to the effect of having alcohol sitting on your follicles for a longer time period -- these studies are in vitro, not in humans, so there's no way to know whether they affect hair growth positively or negatively. Minoxidil dilates blood vessels by working as a free radical (nitrous oxide, which has an unpaired electron).

In a one year time span, 5% is more effective than 2% and microneedling with minoxidil seems to have an effect. Here's an odd quote from that 4th study:

I don't know that there's a study looking at usage with @mxnprettynice's protocol of using a hat specifically, though presumably one that's waterproof would allow the minoxidil to stick around longer:

Also @duchaine makes an excellent point. PRP, minoxidil or pretty much any hormonal/non-hormonal treatment for hair will have different effects depending on age because they all, to one degree or another, use inflammation as a tool. Inflammation has profoundly different effects across the lifespan because the follicles themselves are physically different and respond differently. Give anabolic steroids to someone in their 70s and they will experience much more aggressive hairloss than someone in their 20s, for example.

But @Der3k7 you had a rhinoplasty while you were still recovering from FUE, and this would be a massive potential source of telogen effluvium/inflammatory stress, both from the surgery and the general anesthesia. Did you see any impact on hair growth?

If not then you have your answer.

Also, based on reading the abstract it says evaporation of the water and alcohol is critical to the absorption of the minoxidil. I believe the drug designers want the water and alcohol to evaporate and leave behind minoxidil crystals on the scalp based on what I read in the abstract. The studies abstracts seem like they’re all the same study on quick glance 

16 minutes ago, consequence said:

I'm not sure which studies @mxnprettynice was referring to but these are a few that popped up after a quick google:

• Minoxidil application study 1 
• Minoxidil application study 2
• Minoxidil application study 3
• Minoxidil with microneedling study

I think the idea is that once the minoxidil crystallizes its "thermodynamic activity" decreases. That being said, ethanol is also caustic and I'm not sure as to the effect of having alcohol sitting on your follicles for a longer time period -- these studies are in vitro, not in humans, so there's no way to know whether they affect hair growth positively or negatively. Minoxidil dilates blood vessels by working as a free radical (nitrous oxide, which has an unpaired electron).

In a one year time span, 5% is more effective than 2% and microneedling with minoxidil seems to have an effect. Here's an odd quote from that 4th study:

I don't know that there's a study looking at usage with @mxnprettynice's protocol of using a hat specifically, though presumably one that's waterproof would allow the minoxidil to stick around longer:

Also @duchaine makes an excellent point. PRP, minoxidil or pretty much any hormonal/non-hormonal treatment for hair will have different effects depending on age because they all, to one degree or another, use inflammation as a tool. Inflammation has profoundly different effects across the lifespan because the follicles themselves are physically different and respond differently. Give anabolic steroids to someone in their 70s and they will experience much more aggressive hairloss than someone in their 20s, for example.

But @Der3k7 you had a rhinoplasty while you were still recovering from FUE, and this would be a massive potential source of telogen effluvium/inflammatory stress, both from the surgery and the general anesthesia. Did you see any impact on hair growth?

If not then you have your answer.

No my nose job was a full year after my ASMED hair transplant my results were already subpar with low yield 

8 hours ago, mxnprettynice said:

Not if the hair is long enough and there is a layer of hair between the hat. It definitely dries out on scalp much slower 

Can you link the study that talks about this?

4 hours ago, consequence said:

Do you have a pen that you recommend in particular? Something like this one?

I tried minoxidil foam in the past but gave it up because it was too messy and sticky, and it gave me facial swelling/red eyes. I may give it another go though, who knows. Oral minox has been a game changer for me.

Thanks for the suggestions!

I really like the minoxidil dropper it allows me to get the end of the dropper right up against the scalp between hairs and I’m able to do it in a way that my hair stays mostly dry and then I comb it after and all the liquid is on the scalp and my hair is still dry and combed and styled as usual I do this in the morning and then apply xyon dutasteride at night 

On 11/5/2023 at 11:14 PM, mxnprettynice said:

Looks good @consequence! some transplants gain density by month seven, so there's potential for even more fullness in the coming months. You might consider trying microneedling with a derma pen. This could potentially revive follicles that are dormant. I began using one at a depth of 1.5mm weekly, starting in the month 2. I was surprised by results within 20 days. Combining topical minoxidil with oral minoxidil can be a good approach as well, especially now if you've started microneedling. This dual therapy has been effective for many people I've seen.

Cialis/Viagra can be particularly beneficial in the early stages of a hair transplant. In my case, I used it since I didn't want to give up nicotine vaping.

Wait why are you guys talking about taking viagra or cialis after a hair transplant in the beginning? Are you guys saying this because of increasing blood flow improve graft survival?