I just started Loniten. I take 10 mg. daily, but since I have chronic high blood pressure, it fits in fine. In fact, I've been on many strong anti-hypertensives and this is the first one that helps me. In fact I could easily go to 20 mg. a day. I take a very low dose of Spironolactone for fluid, even though my doctor said 10 mg. of minoxidil usually doesn't bother younger people! You will be sure to hear from me if Loniten works.