Senior Member mmokin Posted January 4, 2022 Senior Member Share Posted January 4, 2022 im sure we've all seen those videos of people use minox and microneedling than growing full beards after a full year. but they are using topical minox which has been shown to be less effective than oral for scalp hair. would this also be true for if you were attempting to grow a beard? Link to comment Share on other sites More sharing options...
Senior Member Ajamilo Posted January 4, 2022 Senior Member Share Posted January 4, 2022 So microneedling and then use oral min? Link to comment Share on other sites More sharing options...
Senior Member mmokin Posted January 4, 2022 Author Senior Member Share Posted January 4, 2022 1 hour ago, Ajamilo said: So microneedling and then use oral min? thats what i would plan doing if i wanted to grow facial hair Link to comment Share on other sites More sharing options...
Senior Member Etownone Posted January 4, 2022 Senior Member Share Posted January 4, 2022 Topical Minoxidil is less effective then oral? I thought that was still up for debate. Link to comment Share on other sites More sharing options...
Senior Member mmokin Posted January 4, 2022 Author Senior Member Share Posted January 4, 2022 41 minutes ago, Etownone said: Topical Minoxidil is less effective then oral? I thought that was still up for debate. wheres the debate can you link me to a source pls? Link to comment Share on other sites More sharing options...
Senior Member Etownone Posted January 4, 2022 Senior Member Share Posted January 4, 2022 40 minutes ago, mmokin said: wheres the debate can you link me to a source pls? https://pubmed.ncbi.nlm.nih.gov/32622136/ Link to comment Share on other sites More sharing options...
Senior Member mmokin Posted January 4, 2022 Author Senior Member Share Posted January 4, 2022 5 hours ago, Etownone said: https://pubmed.ncbi.nlm.nih.gov/32622136/ But this isnt a study that is saying which is better its just saying it can work as an alternativr which we already know Link to comment Share on other sites More sharing options...
Senior Member Etownone Posted January 4, 2022 Senior Member Share Posted January 4, 2022 13 hours ago, mmokin said: im sure we've all seen those videos of people use minox and microneedling than growing full beards after a full year. but they are using topical minox which has been shown to be less effective than oral for scalp hair. would this also be true for if you were attempting to grow a beard? I'm just trying to get some clarification here bud.. Because u said: "but they are using topical minox which has been shown to be less effective than oral for scalp hair." If this is true, which this is the first time I heard this, then I'm switching to oral. Link to comment Share on other sites More sharing options...
Senior Member JDEE0 Posted January 4, 2022 Senior Member Share Posted January 4, 2022 (edited) 12 minutes ago, Etownone said: I'm just trying to get some clarification here bud.. Because u said: "but they are using topical minox which has been shown to be less effective than oral for scalp hair." If this is true, which this is the first time I heard this, then I'm switching to oral. Oral minoxidil will be more effective overall, yes. It's not necessarily a catch all truth for everyone, but the problem with topical for many people is that they genetically lack the necessary sulfotranferase enzyme in the scalp that is needed to convert minoxidil into minoxidil sulfate; the drugs active form that actually aids hair growth. With oral minoxidil, the liver processes things instead and largely bypasses this issue so it doesn't really matter if someone lacks the enzyme on the scalp very much. If you happen to be someone who has said enzyme in abundance, then topical will work just fine and there's less of a need to use oral/it won't be drastically more effective to begin with. But many people see little success with topical for the above reason. Edited January 4, 2022 by JDEE0 1 Link to comment Share on other sites More sharing options...
Senior Member mmokin Posted January 4, 2022 Author Senior Member Share Posted January 4, 2022 13 minutes ago, Etownone said: I'm just trying to get some clarification here bud.. Because u said: "but they are using topical minox which has been shown to be less effective than oral for scalp hair." If this is true, which this is the first time I heard this, then I'm switching to oral. minoxidil needs to be turned into minoxidil sulfotransferase to do anything since its a prodrug, the skin can do this to a varying degree but if taken orally it is converted into the sulfate form in the liver. im pretty sure this is why its more effective than topical but was looking for a study to confirm this Link to comment Share on other sites More sharing options...
Senior Member mmokin Posted January 4, 2022 Author Senior Member Share Posted January 4, 2022 4 minutes ago, JDEE0 said: Oral minoxidil will be more effective overall, yes. It's not necessarily a catch all truth for everyone, but the problem with topical for many people is that they genetically lack the necessary sulfotranferase enzyme in the scalp that is needed to convert minoxidil into minoxidil sulfate; the drugs active form that actually aids hair growth. With oral minoxidil, the liver processes things instead and largely bypasses this issue so it doesn't really matter if someone lacks the enzyme on the scalp very much. If you happen to be someone who has said enzyme in abundance, then topical will work just fine and there's less of a need to use oral/it won't be drastically more effective to begin with. But many people see little success with oral for the above reason. you mean less success with topical in the last sentence? Link to comment Share on other sites More sharing options...
Senior Member JDEE0 Posted January 4, 2022 Senior Member Share Posted January 4, 2022 Just now, mmokin said: you mean less success with topical in the last sentence? Yeah, sorry, already edited it before you replied but you must've quoted it before it went through Link to comment Share on other sites More sharing options...
Senior Member Etownone Posted January 4, 2022 Senior Member Share Posted January 4, 2022 So there isn't any data or studies to confirm oral is more effective then topical. That's all I needed to know. Thought I was going to have to switch to oral. Thx. Link to comment Share on other sites More sharing options...
Recommended Posts
Create an account or sign in to comment
You need to be a member in order to leave a comment
Create an account
Sign up for a new account in our community. It's easy!
Register a new accountSign in
Already have an account? Sign in here.
Sign In Now