ICX-TRC - Phase II trial status

[Rahul_39]

Hi There,

 

Probably useful info from intercytex phase 2 trial results. Does look like some efficacy in their R&D programme.pre-stimulation of epidermis prior to injection of DP cells have resulted a crackering 105% hair growth. 2 lost to study( probably out there with their gfnds hanging around )

 

Anyways here you are::

 

"?? Efficacy trials designed to look for new hair growth

"?? Rolling programme to optimise delivery technique

"?? 12 patients treated (2 lost to study), preliminary data encouraging

"?? 2 main variations on delivery technique assessed;

??“ Group 1 (no pre-stimulation of epidermis) - at 24 weeks 2 out of 5 patients

showed significant increase in hair counts (21 & 55%)

??“ Group 2 (pre-stimulation of epidermis) - all 5 patients showed significant hair

increase (13 ??“ 105%) [6 and 12 week data]

"?? Stimulation of epidermis prior to injection appears to improve results

"?? Further improvements in delivery technique planned for next 8 patients

"?? New IP being generated

 

Best Regards,

Rahul

[Rahul_39]

Hi There,

 

Probably useful info from intercytex phase 2 trial results. Does look like some efficacy in their R&D programme.pre-stimulation of epidermis prior to injection of DP cells have resulted a crackering 105% hair growth. 2 lost to study( probably out there with their gfnds hanging around )

 

Anyways here you are::

 

"?? Efficacy trials designed to look for new hair growth

"?? Rolling programme to optimise delivery technique

"?? 12 patients treated (2 lost to study), preliminary data encouraging

"?? 2 main variations on delivery technique assessed;

??“ Group 1 (no pre-stimulation of epidermis) - at 24 weeks 2 out of 5 patients

showed significant increase in hair counts (21 & 55%)

??“ Group 2 (pre-stimulation of epidermis) - all 5 patients showed significant hair

increase (13 ??“ 105%) [6 and 12 week data]

"?? Stimulation of epidermis prior to injection appears to improve results

"?? Further improvements in delivery technique planned for next 8 patients

"?? New IP being generated

 

Best Regards,

Rahul

[Badger]

Hey Rahul_39

 

When you say 105 %, what do they mean.

If i was given an empty pint glass, and suddenly the bar man gave me a 105 % top up in that pint glass, i would expect to have a pint glass that s more then full.

 

In this experiment does it mean that the part of the scalp that was treated showed a 105 % increase in hair growth i.e. full original density on the test site???

[Pat - Community Publisher]

Rahul_39

 

Where did you the above information regarding the phase 2 trials being done by Intercytex?

 

I visited Intercytex this past spring and I have been following the phase 2 trials. I'm not aware of any results being presented to the public.

 

I'd be curious to know where you got this info.

 

Best wishes, Pat

[Rahul_39]

Badger,

 

Percentages according to me is not the best way to actually assess the hair growth(atleast for the wider hair loss fraternity). i was expecting something like haircounts. Anyway based on my calculations

 

lets say you have a bald area

 

it is about 4 inches by 4 inches

it has 20 hairs on it.........................

 

200percent regrowth, which you say is the best HM has shown, would be 40 new hairs in this area.

 

see anything wrong in this picture?

 

Pat,

 

I have been following Intercytex, Aderans, Acell(though they work on veternary products) closely

Just for info, Acell powder had showed some signs of hair growth on skins of animals where there was no hair before(after using Acell powder in the wounded area). so to cut it short, we wound the bald area say with gentle needling and spray some ACell powder to see the new growth(this is still in its infant stage though).

 

As far as intercytex results are concerned,

Interim results for six months ended 30 june 2007 is released on 25th september 2007.

<<http://www.intercytex.com/icx/news/releases/2007/2007-09-25>>

 

Info i extracted was from the following PDF.

<< http://www.intercytex.com/icx/investors/rep/rep2007/200...07-09-25.pdf>>

 

Cheers,

Rahul

[Pat - Community Publisher]

Rahul,

 

Thanks for this info and the clarification. I do agree that their reporting is very hard to understand. I find it vague. My sense is that since the company is still raising funds they are putting the best face possible on their current results.

 

But 100% or 200% increases on next to nothing don't amount to much.

 

Thanks again, Pat

[HTinthefuture]

I read trial II could take up to 3 years, but also heard all trials will be done by 2010, so who knows. also, like HT, once it goes to market, it will take 3-5 years to perfect it and to get enough surgeons on board. it will no doubt drive the prices of HT down as the reality of this comes closer though.

[omar77]

This must seem very stupid but because English is not my mother language I really haven't understand it yet.The question is with this new method the hair that is going to grow will be 100% real or like transplated meaning a little fake?

[hairdude83]

2010 blah, whats the point of gettin it than, probably go half bald.. lol think about about the present now 1-2 years.. any new drugs coming out next year sometime >?

[Rahul_39]

hi guys,

 

there are few companies and individuals in pipeline who can spell out the ground breaking news at anytime. I am keenly waiting.

 

Here you are..

1. Intercytex (Paul Kemp et al.)

2. Follica, Inc. (George Cotsarelis, Elaine Fuchs et al.)

3. Aderans (Ken Washenik et al.)

4. PhoenixBio (??)

5. Shishedo (??)

6. Acell, Inc (??)

7. Hair Research Laboratory, University of British Columbia (Kevin McElwee)

8. Zhejiang University, China (Lu Zhongfa)

9. Big Pharma (e.g., Merck, Pfizer, etc)

10. Gho Clinic (Coen Gho)

 

 

PS:- The above list is a copy/paste from other site. So i don't take the credit

 

Cheers,

Rahul

[omar77]

1)Can somebody please answer my previus guestion?

2)I visit the site of this Gho Clinic (Coen Gho)and it talks about HT without scar,not FUE something else,it also has some strange photos. Does anybody knoa something about this technic?

[omar77]

"knoa" that's know ok?

[Rahul_39]

Omar,

 

You are going to grow real hair on ur head if ICX-TRC is commercialised.

 

Derma Papilla cells are extracted from back of your head and cultivated in vitro and then injected back to recipient areas where there is thinning or no hair. Phase 2 trials had shown some efficacy and they have seen some hair growth in their clinical results on patients.

 

 

So its going to be natural. Initially they were not sure about the orientation of the newly sprouted hair, but now if you check the latest intercytex patents, you can see that they have found a way to inject the cells in such a way that orientation will no longer be a issue(they talk about a robot to do the same here).

 

I had visited the site of GHO sometime back and sent them a mail asking for their clarification. I posted that mail in this forum sometime back. I think we need to look at more before/after pics of the patients from GHO before actually considering it as a viable option.

[Tom R.]

It seems like one of our new coalition doctors is/was involved in the Phase II trials. I surfed the Intercytex website and saw this..."A Phase II clinical efficacy trial on patients with male pattern baldness is being conducted by Dr Bessam Farjo in Manchester, to optimise the delivery of DP cells."

[omar77]

Thanks man.