Badger

Thats interesting, Hard to know from reading it if its gonna be a significant breakthrough or just turn out to be a farce. Whats promising is the application of WNT proteins which correlates with Follica's work which seems to be a lot more publicised and credable. I thought i read a while ago that Follica have begun trials, but i could be wrong. Maybe its that they're starting trials in early 2009. Subsequently, Follica announced in April 2007 that if everything went exceptionally well, they'd have a product by April 2009, but if this was the case we d probably have heard something by now.

This statement appeared a while back in regard to Follica's future Stem Cell endeavour. It was made by David Steinberg who is a profiled member of Follca featured in the company Bio on their website. This statement can be refernced http://www.xconomy.com/2008/01/04/gone-today-hair-tomor...aldness-treatment/2/ David Steinberg 1/4/08 2:12 pm I am with the company. While we have not tested this in humans yet we fully expect that hair will persist. There are multiple reasons for this. First of all, consider hair transplants - while they have other flaws, the hair does indeed persist despite the presence of circulating DHT. In a distinct, but similar way, the Follica treatment changes the microenvironment of the follicles. Further, a single hair cycle lasts several years, and at the very least the new hair should last one full cycle (because of the underlying physiology of the condition). Also, circulating levels of DHT actually drop over a man's life. We have seen numerous clinical reports of patients showing sustained hair cycling when exposed to conditions similar to the treatment Follica is pursuing (in a carefully directed and controlled way). What do you's think. Can anyone understand how the hairs would be DHT resistant. I wonder how would the follica treatment change the micro-environment of the follicles. Any thoughts????

Thats pretty interesting stuff. Id imagine that gene therapy is way off in the future however and will have all sorts of ethical road blocks to breakthrough before it becomes a reality.Im not talkin from any experience or prior research mind you. What if the treatment went all wrong and instead of gettin new hair we got loads of fingers growing out of our scalp. That would really suck.

Hey jupiter, I hear you dude. It does suck. If its a cure your interested in, your not the only one. I think they'll have one in the next ten years from what i ve read. i haven't heard any up dates other than whats goin on in pennsylvania university. The best thing about it is that the whole procedure which they're hoping to start testing on humans in 6 months to a year uses already proven and approved medical procedures. This means that its not some space age, genetic, star trek shit. What they're working on sounds practical. Badger I started loosing my hair around 20...i know how you feel.

hey, I heard all about that to. Im no expert but id imagine it will help. I heard that that study involved that a sample cell and injecting into 4 different genes into into it. From this they reckon they could make brain tissue, a new heart etc. It was called the Holy Grail of Medicine. Its only a guess but theres a good chance it will have great applications for treating baldness.

Here we are again i.e. within 5 years.... why is it always 5 years away with every hairloss treatment. Why not 7 years or 4 years. But if he's tellin the truth, it would be great.

Hey Rahul_39 When you say 105 %, what do they mean. If i was given an empty pint glass, and suddenly the bar man gave me a 105 % top up in that pint glass, i would expect to have a pint glass that s more then full. In this experiment does it mean that the part of the scalp that was treated showed a 105 % increase in hair growth i.e. full original density on the test site???

I stopped using Rogaine (Minoxidil) a year ago. My scalp got really flakey and dry plus it didn't seem to be slowing down hair loss or re growing anything. I cannot say if Minoxidil is the culpritbut, but since last year i have been suffering from Dermatitious in the exact same position of my scalp i used to apply Rogaine. I have been on 3 courses of Antobiotics and its nearly better (1 year later). Thats the reason why i stopped using Minoxodil. But don't let me influence you, everyones skin is different, and mine is really sensitive. You should see me after i have a shave.

I think they re still in phase 2. They're actually due to publish some results soon from what i ve read. They still aim to launch a product in 2009. No one knows whats goin on there really. People generally aren't to excited on the forums from what i ve read. There s a lot of scepticism. But i read recently that intercytex managed to clone a patch of human skin and effectively attach it to someones arm and it fully integrated into the body. No signs of rejection. That s the completion of phase 3 of some other skin repair treatment. http://www.avlar.com/news.113.htm That does sound encouraging to me. If they can clone skin now, then how close would they be to cloning a patch rear scalp skin along with the all important hair follicles and glands. If that was the case then you could have a hair transplant without having to get the back of your scalp cut and removed plus you would have all the doner hair you require. Anyway, who really knows.

I e mailed them and asked them the same question a while back. This is the response i got: Thank you for your interest in Follica. We are extremely excited about the research and are working diligently to translate the findings into clinical treatments. We cannot anticipate precisely when this will be launched as a commercial product, nor have we announced any specific clinical trial plans at this time, though we hope to conduct initial testing in humans soon. We are not currently tracking potential volunteers or creating a distribution list, but please feel free to check back in 6-12 months. We look forward to announcing additional information as we progress. We know how much this means to so many people, and are focused on making it a medical reality. Best regards,

I wouldn't say anything to the kid. When i was sixteen in Biology class back in school (12 years ago), i had a biology teacher who could predict who in the class would go bald when they were older. Back then i had long hair, it was brush thick as well. I was known in the class as Jesus. Anyway, he went from desk to desk and sniggered at the people that would go bald. He was right about me. One of the other lads he sniggered at that day is bald now as well. At the time i laughed it off. But he was right. But the point is what difference will it make if you tell a person or not. We can't do an awful lot about it. I recently heard on the radio that you can predict if someone will encounter hair loss as early as the age of 10. Some boys at that age have a higher hairline and more of a horse shoe shape to their hairline. I ve also heard that certain haircolours in this case are more suseptable to encounter hair loss.

I came across this recent article which i thught was encouraging. Thought id share it with you's. It doesn't relate specifically to hair cloning but sounds like sonething that could help it become a reality. Here's the link. http://www.avlar.com/news.113.htm

That Kiely fella sounds like a Spa....

Hey Hungry Hoss, Your doing the right thing. You 've got some good advice. I myself live in Dublin. Initially i wanted to get a hair transplant in Ireland but after much research i decided to look at doctors in America. A year later and im still researching. I looked at doctor Kiely's site/Blackrock clinic and felt very inticed. Pat the publisher visited Blackrock clinic and was very impressed by Dr Collins work. Pat said in a posting that the only reason why Dr Collins is not a recommended surgeon on the site was because of the laws in Ireland preventing Pat from listing an Irish Surgeon. But Blackrock clinic is ubber expensive. 10 Euro per graft. Thats a lot of money. You d pay a quarter of that per graft in the states. I know what its like, i think everyone on this site understands the anxiety and frustration associated with hair loss.It sucks. But take your time bud. While some doctors are great, other people in this industry don't give a flying F**K about the well-being of the patients. Badger

HDLB Did you say 2008 for a release date earlier on. How optimistic would you be personally about neosil having a product by next year. I wonder how effective it would be when it comes out. Who knows if used in conjunction with the androscience compound if it makes it out of the lab along this wnt dermebrasion treatment if it to acquires fda approval could all together work as a cure.

Here a few links i found that may shed light on the Neosil research. What their proposed treatment involves. http://www.regrowth.com/hairloss-remedy/neosh101/neosh101-osh101.cfm http://www.regrowth.com/hairloss-remedy/neosh101/neosh101.cfm http://www.regrowth.com/hairloss-remedy/neosh101/neosh101-neosil.cfm

This is something i found there a while back. Some of you are more then likely already aware of it. RU 58841 is an anti androgen that binds to the hormonal receptor sites on the follicles, and prevents the binding of Dehydro-Testosterone. Its "affinity" to the receptor sites is much stronger than that of the hormones, making it very effective. This is why RU 58841 holds a great deal of promise as a hair loss treatment. Lack of financial potential is probably the reason for the limited extent of research done on it so far. As long as there is no considerable research conducted, it is unlikely it will become widespread and accessible hair loss treatment. Getting a hold of it at this time is very difficult, and those who succeed pay a great deal of money for it. In the Research and studies section there is reference to research that tested the effectiveness of RU 58841 in macaque Androgenetic Alopecia, and the pictures in it practically speak for themselves. Faith-Eagle (http://www.faitheaglepharm.com) is a Chinese lab that produces RU 58841 by or

This sounds pretty cool, The fact that there are no, as yet known side affects makes this seem within reach. I can't help to wonder what kinds of results the clinical phases will yield. No doubt they'll vary among different individuals. Who knows, used in conjunction with minoxidil, and or wnt/dermabrasion treatments (when/if theat happens), could really bring about regrowth. This could be good. This sounds like that drug they were developing in France in the 90's, RU 48871.

Im kinda in the same boat as you. Considering a HT, but still unsure. I don't know what i ll do. Its still out of my price range. But aside from that, hypothetically, if they were able to cure, or at efficiently treat hairloss in say 5 or 6 years time, would it be worth it getting a hair transplant now. Could we wait a few years and see whats gonna happen in terms of wnt protein/dermabrasion treatment, or hair multiplication. I wouldn't imagine getting a hair transplant would affect any future viabability for someone to undergo hair multiplication treatments. But im no expert. On the other hand wnt protein/dermabrasion treatment could be a different scenario. Its hard to know if by wounding the skin now getting implants on the recipient from the donor areas will prevent the success or the effeciency of this termed "embrionic window". I doubt anybody can give you an answer to that one. Who knows all these potential cures could flop and never make it out of the lab. But im extremely hopeful.

Hey Hlbd, Sorry if i got my wires crossed. I read a load of different articles. I think its interesting. The researchers are saying it may translate into a treatment in over 5 years. They also said in another, admittably being overly optomistic, possibly 2-3 years. Who knows. They said they will be looking at the genes involved and hope the future treatment won't involve making wounds. Don't know what that means. At least there's hope. There s a lot of hoopla about this breakthrough. Its been in the news, radio and internet. Perhaps theres some level of credability to all this....we'll see. Always good to hear from you HLBD, you understand all this science stuff. Your a good interpreter.

Sorry guys, Have a look at these two different links. They seem to be two seperate studieson mice that induce hair using the wnt protein. Or am i mistaken. The later one seems more like the curis results and have potential risks. tell me what you think.... http://www.sciencedaily.com/releases/2007/05/070516133023.htm http://www.innovations-report.de/html/berichte/biowisse...e/bericht-18476.html

Hi, From a reading of a few articles on the work with the wnt protein it seems that the potential to cause several types of cancer exists. Plus the researchers think that although it is a breakthrough, it is still years off from treating mpb. Curis swere a lot more optomistic. Badger

Yeah it was just on the news that the research has ended due to the potential of causing cancer. This thread is from about 2 weeks before that news came out. Its an awful pity. HLBD goes into some detail as to why in another thread. Go into the find option on the main menu and type "curis hedgehog signaling pathway". Its all there

El Guapo I got a consultation with the Body Clinic in Dublin. I saw an add in the paper about laser treatment to restore hair. I got the exact same explanation, The super new powerful laser would blast through the caked up DHT that was strangling my hair follicles to death. At that point i knew very little about DHT and the science of hair loss. I found the consultant condecending and smug. He told me i had a load of dead follicles, and he would do his best to regrow my hair. Luckily i declined his treatment. Then he offered to do a hair transplant

That sucks. F**ken Cancer. I hate it. Ah well, it was interesting to learn about the curis work though. At least the research is being done. At least they found this out now and not when people started using their proposed treatment. Like the way we keep using mobile phones and microwaves while ambiguity remains whether or not they cause tumours. Thanks for the info HLBD. Maybe hair cloning isn't such a bad idea after all.