I got it from XYON I switched to their topical dutasteride this week. Below is a post from their patent studies. It’s super impressive.
So average ranges of DHT range from 0.38 to 3.27 nmol/L. Just so we understand.
Ok so after reading the results. This is how it’s broken down.
Table 9 is looking at serum concentrations by the hour on day 28. That’s why you’re seeing an increase in serum DHT levels. So 1 hour after application the DHT levels drop than go back up after a 24 hour-period based on this graph.
But for some their DHT levels are higher after application and gradually decrease after a 24-hour period. This reflects normal day to day fluctuations of testosterone and DHT.
The graph you want to look at is table 10 which tracks DHT serum levels from day 1 hour 0 (baseline) to day 28 hour 24.
Graph 10 subject 1. He was 1.132 at day 1 0 hours or (baseline). On day 28 (24) hours, his levels were 0.981. A 0.151 difference, which equals 15.1%. That means his DHT levels decreased by 15% at the end of 28 days.
Only three subjects saw an increase in DHT, which were both still low in the average range. Subject 6 started at 0.317 (below average range) by the end he was at 0.693. Slightly above the 0.38 average.
Subject 8 baseline was 0.517 by day 28 he was 0.911. Subject 10 started off at 0.928 and ended at 1.118.
Now if you look at these results at face value you might think, the dut made DHT increase. But I don’t believe thats true, to me, this looks like 3 subjects had no decrease in DHT levels. Their levels fluctuated, as they do normally without any medication.
For some reason table 11 looks at day 1 4h as the baseline instead of day 1 0h. This skews things, you’ll see some participants levels decreased and some increased after day 1 4 hours, so it makes their increase/decrease look higher. If you look at the baseline day 1 0 hour. You’ll see the differences were negligible.
Overall, the average decrease is around 10-12% depending on whether you look at baseline being 0 hour or 4 hours. This is WAY better than finasteride. No doubt about it. Its not even close.