Regular Member KulMD Posted November 21, 2007 Regular Member Share Posted November 21, 2007 I have read several accounts stating that Rogaine's half life may support once a day dosing. Any thoughts? The quote below is from Dr. Bernstein: Once a day topical use of Rogaine (topical minoxidil 2% and 5%) seems to be almost as effective as using it twice a day. The reason is, that although minoxidil has a relatively short half-life of several hours when given orally, when topically applied, it has a half-life of 22 hours in the skin. This suggests that once a day dosing is a reasonable option. It is important to realize that Pfizer, the company that now makes Rogaine, specifically states that it will be less effective if used only once a day." Link to comment Share on other sites More sharing options...
Senior Member wylie Posted November 22, 2007 Senior Member Share Posted November 22, 2007 Excellent information and thanks for that, I tend to agree with this assessment, or have at least hoped it was true. Lets hope the good doctor is right. Link to comment Share on other sites More sharing options...
Bill - Seemiller Posted November 23, 2007 Share Posted November 23, 2007 KulMD, I have heard this before as well. I know many who use minoxodil only once a day and it seems to be effective for them. Based on this information, it may be a good thought to start with once a day to see if it has any benefit for 4 months or so and if no benefit is seen, try 2 times a day for a few more months. Bill Link to comment Share on other sites More sharing options...
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