Visiting World Congress on Hair Research, UK to improve on HM @ Dr. Nigam's - Agenda

[Drnigam]

Visiting WCHR 2013, UK to improve on HM – Agenda @Dr. Nigam’s

 

My agenda for 7th World Congress on Hair Research, 4th – 6th May 2013 would be seeking answer for following questions by meeting concerned researchers and discussing with them during their presentations. Let me see if I can get video interviews, discussions for you all. All my member friends can also post your questions related to stem cell hair multiplication, DP Cells Injection, DP culture, etc which I might have missed.

 

I will be in Edinburgh from 3rd – 6tth May & 10th & 11th May 2013, I will in London from 7th – 9th May 2013.

One member from Netherland will be coming to attend the conference, he is a bio-tech and has been helping me a lot may be I will sponsor him partly.

 

Questions:-

1. Hair follicle epithelial and mesenchymal stem cells interaction and communication to create a new hair follicle in-vitro or in-vivo. Would like to discuss more with Jahoda regarding his organ germ method culture for the same.

 

2. Trichogenic DP culture, Cohesive DP Structure, In capsulated DP Cells, ECM secreting aggregates of DP cells.

 

3. How to increase the healing of bisected follicle without the Dermal Papilla?

 

4. How potent are freshly isolated DP cells from body hair kept in DP culture medium?

 

5. The in-vitro follicle bisection, what is the minimum requirement for re growth in the bisected follicle (Bulge stem cells + outer root sheath & / or dermal cup sheaths stem cells &/or hair germ matrix epithelial stem cells)?

 

6. The best method in culture medium for DP culture that is 3D culture hang-in-drop method, how to get a intact basal lamina?

 

7. Role of repeat injection of Growth Factors in-vivo for activating dormant follicles &/or creating new follicles.

 

8. Better ways to counter the effects of DHT on Dermal Papilla via TGF-BETA1, how to block or slow down the follicle miniaturization?

 

9. What difference in hair follicle neogenesis we can expect viv-a-vis multipotent adult hair follicle stem cells vs pluripotent embryonic stem cells? How effective wil be the conversion of multipotent adult hair follicle stem cells to pluripotent embryonic stem cells? How will HM improve if at all by conversion of multipotent adult hair follicle stem cells to pluripotent stem cells and subsequent differentiation?

 

10. What is my favorite researcher Jahoda’s experience on trans-gender hair transplant and how to achieve optimal results with eye-brow like pluck hair transplant with or without associated Dermal Sheath?

 

11. How many of these researchers are open to do small clinical experiment on their research findings at Mumbai, India in association with my Clinic & Lab to take advantage of my existing permission regarding stem cell research and software regulations in India?

 

 

I want to focus on following research papers and subsequent Q&A discussions from 4th – 6th May 2013, Edinburgh, UK:-

 

1. Update on dermal papilla culture systems

Young Wang Sung, Republic of Korea

2. Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches

Koh-ei Toyoshima, Japan

3. Classic perspectives on human hair follicle organ culture

Michael Philpott, UK

4. Intermediate hair follicles: a more clinically relevant hair follicle model

Ben Miranda, UK

5. Tissue Engineering and Regeneration

Chairs: Mike Philpott, Bruno Bernard, Kurt Stenn

 

P217 - Full-thickness skin with mature and cycling hair follicles using tissue culture expanded human cells

X Wu, L Scott, K Stenn

Aderans Research Institute, Inc., Marietta, United States

 

P218 Enhancing hair follicle neogenesis in bioengineered human skin substitutes

R Thangapazham1, P Klover1, S Li1, J-A Wang1, Y Zheng2, L Sperling1, G Cotsarelis2, T Darling1

Uniformed Services University of the Health Sciences, Bethesda, United States,

2University of Pennsylvania, Philadelphia, United States

 

P220-Human hair follicle neogenesis using microenvironmentally reprogrammed dermal papilla cells

CA Higgins1, CA Jahoda2, AM Christiano1,3

1Dermatology, Columbia University, New York, United States, 2 Biological and Biomedical Sciences, Durham University, Durham, United Kingdom, 3Genetics and Development, Columbia University, New York, United States

 

P221 Calcium microcapsule: a possible scaffold for building artificial dermal papillae

C-M Lin1, K Huang2, Y Li3

1Shantou University Medical College, Shantou, China, 2S. Gallicano Dermatologic

Institute (IRCCS) Second Affiliated Hospital, Shantou University Medical College,

Shantou, China, 3First Affiliated Hospital, Shantou University Medical College, Shantou,

China

 

P222 Human scalp derived fibroblasts are multipotent and trichogenic

X Wu, K Watkins, K Stenn

Aderans Research Institute, Marietta, United States

 

P044 The therapeutic potential of naturally immune privileged hair follicle cells

X Wang, J Hao, G Leung, T Breitkopf, Z Ao, G Warnock, J Shapiro, K McElwee

University of British Columbia, Vancouver, Canada

 

8:30-Concurrent Session: 3 Sidlaw Auditorium

Stem Cells and Epigenetics

Chairs: George Cotsarelis, Vladimir Botchkarev, Denis Headon

 

P186 Topology-dependent plucking leads to more regenerating hairs than plucked via extra-follicular macro-environment modulation

C-C Chen1,2,3, L Wang4, TX Jiang1, S Shi4, CM Chuong1

1Pathology, University of Southern California, Los Angeles, United States,

2Department of Dermatology, Taipei Veterans General Hospital, Taipei, Taiwan,

Republic of China, 3Department of Dermatology, Yang ming University, Taipei, Taiwan,

Republic of China, 4Center for Craniofacial Molecular Biology, University of Southern

California, Los Angeles, United States

 

P187 Competitive balance of Intra-bulge BMP/WNT signaling reveals a robust gene network governing stem cell homeostasis and cyclic activation

E Kandyba1, Y Leung1, Y-B Chen2, R Widelitz3, C-M Chuong3, K Kobielak1

1Eli and Edythe Broad Center for Regenerative Medicine & Stem Cell Research,

Department of Pathology, University of Southern California, Los Angeles, United States,

2Norris Medical Library, University of Southern California, Los Angeles, United States,

3Department of Pathology, University of Southern California, Los Angeles, United States

1030 Plenary Symposium 1: Pentland Auditorium

An Update on Hair Follicle Stem Cells

Chairs: Satoshi Itami, Rod Sinclair

 

PS1.1 Hair follicle stem cells in alopecia

George Cotsarelis, USA

 

PS1.4 Cellular and signaling mechanisms that regulate hair follicle stem cells by live imaging

Valentina Greco, USA

 

PS1.2 Mechanisms of hair follicle aging and stem cell regulation

Emi Nishimura, Japan

 

PS1.3 Biological and translational potential of hair follicle mesenchymal cells

Colin Jahoda, UK

 

1200 Keynote Lecture Pentland Auditorium

K1 Skin Stem Cells: In Silence and in Action

Elaine Fuchs, USA

 

1600 Concurrent Session 5: Pentland Auditorium

Androgenetic Alopecia and Hair Restoration

Chairs: Ramon Grimalt, Nilofer Farjo, Venkataram Mysore

 

P039 What is the meaning of the “visible pigmented non-vellus hair count” in FDAapproved clinical trial reports?

DJJ Van Neste1,2, HD Rushton3

1Skinterface, Tournai, Belgium, 2Brussels’ Hair Clinic, Brussels, Belgium, 3School of

Pharmacy & Biomedical Sciences, University of Portsmouth, Portsmouth, United

Kingdom

 

P040 Pharmacodynamic of P-3074 (finasteride 0.25% topical solution) in subjects with androgenetic alopecia

M Caserini1, R Palmieri1, M Radicioni2, E Terragni2

1Polichem S.A., Lugano, Switzerland, 2Cross Research S.A., Arzo, Switzerland

 

 

P041 Genetic variations associated with efficacy of dutasteride, the dual 5a-reductase inhibitor in the treatment of male pattern hair loss

SJ Jo1,2, A Rhie3,4, S Lee3,4, B-L Lew5, W-Y Sim5, KH Cho1,2, JH Chung1,2, J-I Kim3,4, OS Kwon1,2

1Department of Dermatology, Seoul National University College of Medicine, Seoul,

Korea, Republic of, 2Institute of Human-Environment Interface Biology, Seoul National

University College of Medicine, Seoul, Korea, Republic of, 3Genomic Medicine Institute,

Medical Research Center, Seoul National University, Seoul, Korea, Republic of,

4Department of Biomedical Sciences, Seoul National University Graduate School, Seoul,

Korea, Republic of, 5Department of Dermatology, Kyunghee University College of

Medicine, Seoul, Korea, Republic of

 

P043 Oxidative stress and cell senescence in androgenetic alopecia (AGA)

JH Upton1, A Bahta1, N Farjo2, B Farjo2, R Bhogal3, MP Philpott1

1Centre for Cutaneous Research, Queen Mary’s University of London, Whitechapel,

United Kingdom, 2Farjo Medical Centre, Manchester, United Kingdom, 3Unilever R&D,

Colworth, United Kingdom

 

P227 New development in unlimited hair follicle transplant

C-M Lin1, K Huang2, Y Li3

1Shantou University Medical College, Shantou, China, 2Second Affiliated Hospital,

Shantou University Medical College, Shantou, China, 3First Affiliated Hospital,

Shantou University Medical College, Shantou, China

 

P046 Platelet-rich plasma promoting hair growth in human hair follicle dermal papilla cells associated VEGF and VEGFR-2

BJ Kim1,2, SY Kim1,2, TR Kwon1,2, YH Lee1, YS Song1,2, K Li1, YW Lee3, CH Huh4, CK

Hong1

1Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea,

Republic of, 2Department of Convergence Medicine and Pharmaceutical Biosciences,

Graduate School, Chung-Ang University, Seoul, Korea, Republic of, 3Department of

Dermatology, Konkuk University, College of Medicine, Seoul, Korea, Republic of,

4Department of Dermatology, Seoul National University Bundang hospital, Seongnam,

Korea, Republic of

 

1600 Concurrent Session 6: Fintry Auditorium

Factors Influencing Hair Growth

Chairs: Ryoji Tsuboi, Julie Thornton, Natalia Botchkareva

 

P126 A novel PPARγ modulator (GMG-43AC) inhibits human hair growth and inflammatory response in keratinocytes, and up-regulates expression of epithelial stem-cell associated keratins, K15 and K19

Y Ramot1,2, A Mastrofrancesco3, E Herczeg-Lisztes4, T Biro4, M Picardo3, JE Kloepper2,

R Paus2,5

1Department of Dermatology, Hadassah - Hebrew University Medical Center, Jerusalem,

Israel, 2Department of Dermatology, University of Luebeck, Luebeck, Germany,

3Laboratory of Cutaneous Physiopathology and Integrated Center of Metabolomics

Research, S. Gallicano Dermatologic Institute (IRCCS), Rome, Italy, 4Department of

Physiology, University of Debrecen, Debrecen, Hungary, 5Institute of Inflammation and

Repair, University of Manchester, Manchester, United Kingdom

 

P127 Influence of oxygen tension on hair growth and cycle and therapeutic potential of systemic normobaric oxygenation

H Kato1, K Kinosheeta1, N Aoi1, K Inoue1, S Itami2, K Yoshimura1

1Department of Plastic Surgery, University of Tokyo Hospital, Tokyo, Japan,

2Department of Regenerative Dermatology Osaka University Graduate School of

Medicine, Osaka, Japan

 

P128 Eplerenone stimulates human hair growth ex vivo

JE Kloepper1, S Klominek1, T Bir?2, N Farman3, R Paus1,4

 

P129 Age related expression changes of WNT signaling associated genes in human hair follicle

SN Kim1, AR Kim1, SY Lee2, WS Park1

 

P130 Human scalp hair follicles possess the enzymes to synthesise prostaglandins and prostamides from phospholipids and contain PGFα in vivo

KG Khidhir1,2, M Shalbuf1, NP Farjo3, BK Farjo3, JW Wang4, DF Woodward4, SM

Picksley1, VA Randall1

 

P131 Closing KATPATP channels in human hair follicles inhibits hair growth, promotes catagen-like changes and alters paracrine signalling; could this be a new therapeutic approach for excessive hair disorders?

H Rahman1, N Farjo2, B Farjo2, V Randall1

 

P132 Effect of hair follicle environment on nanocarriers stability and drug release properties

F Rancan1, S Hadam1, Z Afraz1, B Bellier2, R Wagner3, C Graf4, J Lademann5, E Ruehl4,

B Verrier6, U Blume-Peytavi1, A Vogt1

 

 

P133 Thyrotropin-releasing hormone (TRH) modulates keratin expression in human skin

Y Ramot1,2, G Zhang2, J Hardman3, IS Haslam3, T Biro4, L Langbein5, R Paus2,3

 

P134 Systemic angiotensinergic stimulation modulates Epithelial-Mesenchymal Transition and collagen deposition in skin and hair follicle

ZP Jara1, M Consolo2, SP Panicker2, K Honda2, P Karnik2, S Karnik1

1Cleveland Clinic, Cleveland, United States, 2Dermatology, CWRU, Cleveland, United States

 

1600 Concurrent Session 7: Sidlaw Auditorium

P145 Trichomegaly, or Hollywood “movie lashes” resulting from mutations in FGF5 and an elongated hair cycle anagen phase

CA Higgins1, L Petukhova1,2, YY Ho1, E Drill1, L Shapiro3, M Wajid4, AM Christiano1,5

 

P146 Detection of chronobiological features on the surface of human hair through the multi-stage analysis of Wilhelmy-force profiles

 

P147 Fractions of cortical cell types correlate with macroscopic bending modulus inhuman hair

T Itou1, Y Ezawa1, S Nagase1, A Mamada1, S Inoue2, K Koike1

1Kao Corporation, Tokyo, Japan, 2Kao Corporation, Wakayama, Japan

 

P148 In vitro assembly of human hair keratin intermediate filaments: Combination of Keratin proteins and their properties

 

P149 ALOX12 inhibitors promote cuticle maturation that affects on hair Texture

K Kizawa1, T Takahashi2, T Fujimori3, R Suzuki2, T Kawai3

 

1600 Psychology and Hair Disorders Workshop Tinto

 

1605 Psychodermatology and psychopharmacology of hair loss

John Koo, USA

Monica Huynh, USA

 

1800 EHRS General Assembly Kilsyth / Moorfoot

1800 KHRS General Assembly Tinto

 

Monday 6 May 2013

0830 Concurrent Session 10: Sidlaw Auditorium Hair Follicle Development, Control of the Hair Cycle and Pigmentation

Chairs: Cheng-Ming Chuong, Emi Nishimura, Desmond Tobin

 

P103 Functional presence of the endocannabinoid system in human hair follicle derived outer root sheath keratinocytes

E Herczeg-Lisztes1, IL Szab?1, A Ol?h1, AG 1, N Vasas1, K Sugawara2, R Paus2, T B?r?1

 

P151 Regulatory T cells increased in the area around and above the bulge of mouse vibrissa follicles in catagen

M Oishi, I Niibe, T Matsuzaki

Biological Science, Shimane University, Matsue, Japan

 

P152 A meeting of two chronobiological systems: Period1 and BMAL1 modulate the human hair cycle

Y Al-Nuaimi1, JA Hardman2, IS Haslam2, T Biro3, BI Toth3, N Farjo4, B Farjo4, M Philpott5, R Watson2, B Grimaldi6, JE Kloepper7, R Paus2,7

 

P153 Reprogramming regular skin fibroblasts into hair inducing dermal papilla cells

C Clavel1,2, A Rezza1,2, M Rendl1,2,3

 

P154 Development of the mouse dermal fat layer is linked to hair follicle development, occurs independently of subcutaneous fat and is marked by restricted early expression of FABP4

K Wojciechowicz1,2, K Gledhill1, CA Ambler1, C Manning1, CA Jahoda1

 

P155 ATM expression in hair bulb melanocytes is a marker of oxidative stress in canities-prone scalp

SK Sikkink1, O Freis2, L Danoux2, DJ Tobin1

P156 Stem cell factor/c-kit signalling in the hair bulb is essential to maintain hair pigmentation in adult human hair follicles in vivo and in organ culture

T Vafaee1,2, TJ Jenner1, SM Picksley1, VA Randall1

 

1200 John Ebling Lecture Pentland Auditorium

 

K2 Hair Follicle: The Root of the Future. Clinical Research, Implications and Advances

Ulrike Blume-Peytavi, Germany

 

CP1 What’s new in clinical hair research?

Abraham Zlotogorski, Israel

 

CP2 What’s new in basic science aspects of hair research?

Sarah Millar, USA

[sapo]

holy molly... there's a lot going on!

[Blake Bloxham]

Looking forward to hearing some updates from the conference.

[Torip]

Dr. Nigam,

How come you do not have any talks in the conference? You claim to be actually implementing hair multiplication procedures with success. Did not you feel you should present your results to others in the field and gain their approval?

[Gary1911A1]

Don't understand much of what you're doing there, but I look forward to your report.

[ritik]

can you please update,what happened in the conference.