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Serum Testosterone “Lower” In Men With MPB


Swimmy

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Serum Testosterone “Lower” In Men With MPB

 

 

As we previously reported, an age related decline in the testosterone to estrogen ratio in favor of estrogen has been shown to disrupt immune synchronization and increase the overall incidence of hair loss, prostate enlargement, and abdominal fat accumulation creating what is clinically termed the “estrogen syndrome”. It is well known that men with enlarged prostates are much more likely to have androgenetic alopecia, or MPB.

 

While finasteride (Propecia/Proscar) decreases serum DHT, it also is thought to increase estrogen which suggests that men over 35 may want to consider using it in conjunction with a systemic aromatase inhibitor such as Chrysin/Piperine (Super Miraforte), Arimidex, or stinging nettle extract, to maximize its hair growth effects and minimize potential side effects (that are listed in the PDR) such as Gynocaemastia (breast enlargement in males), sexual side effects, and an increase in fat deposition. These compounds have been reliably shown to increase testosterone and reduce excess estrogen, resulting in a youthful hormone profile that optimizes immune function and to some degree, body composition

 

Those contemplating testosterone replacement therapy who are also concerned about hair loss would be advised to use testosterone only in conjunction with a 5-alpha-reductase inhibitor and, possibly and aromatase inhibitor as well.

 

 

Following are excerpts of abstracts after a basic review of the medical literature:

 

* At the Veterans Administration in Los Angeles? they proved in men that no matter how low they made the testosterone levels fall it did not inhibit the prostate cancer growth.

* At the Imperial Cancer Research Fund in London? doctors gave mice huge doses of testosterone and could not get their prostates to grow.

* At the Medical College of Virginia in Richmond? men were measured for serum testosterone levels and no difference could be found between prostate cancer patients and normals.

* At the Harbor General Hospital in California it was shown that testosterone itself competes for binding in the prostate against DHT. When testosterone levels fall more DHT successfully binds thus causing dysfunction and DHT accumulation. A similar process is thought to occur in androgenetic alopecia.

* At the Leeds Medical School in England human prostate BPH tissue was shown to be deficient in testosterone yet had excess DHT levels.

* At the University of Innsbruck in Austria doctors found the lower the testosterone as men aged the higher the BPH,MPB and cancer, and individually higher testosterone levels were unrelated to disease.

* Again at the Leeds Medical School in London the same doctors did another study and found men with individually higher androgen levels did not have higher rates of disease of the prostate. As men aged and their androgen levels fell BPH and cancer rates rose dramatically to parallel the change.

* At the Institute of Endocrinology in Russia doctors found test animals with prostatitis have low levels of blood testosterone and androstenedione.

* At the Bicetre Hospital in France researchers made the point in laboratory animals very clearly where testosterone supplementation kept the prostates small and youthful, while the untreated animals prostates grew with age.

* At the Granada Medical Facility in Spain 104 men with BPH had lower testosterone levels compared to healthy men. Studies like this should leave no doubt in your mind that testosterone is your friend and low levels of it are pathological.

* At the Tenous Cancer Research Institute in Wales researchers found low testosterone in prostate cancer patients using saliva testing.

* At the Moscow Medical Institute in Russia doctors studied the hormone levels of men over 60 and found those with prostate cancer have much lower testosterone levels and higher estrogen levels giving a very low testosterone to estrogen ratio.

* At the Landeskrankenanstalten Urology Clinic in Austria men with BPH or prostate cancer had no higher testosterone levels than healthy men.

* At the Institute of Cancer Research in Norway doctors found that supplementing aged rats with testosterone reduced 5-alpha reductase activity and increased prostate enzyme activity generally leading to healthier functioning and metabolism.

* At the Polish Urology Clinic in Bialystok15 doctors consistently found low testosterone in men with BPH and MPB.

* At the Principe Hospital in Spain men with prostate cancer had low testosterone levels compared to healthy men as verified by both serum and saliva testing. Again at the Principe Hospital another study confirmed these findings with another group of men.

* In China, 18 doctors studied men with BPH and MPB and found consistently low levels of testosterone generally.

* A most important study done at the famous Johns Hopkins University in Baltimore19 men with BPH and prostate cancer were compared to healthy men and it was found testosterone levels were unrelated to progress or severity of the disease. This study was done by some of the foremost doctors in the country and published in the most important of all medical journals regarding prostate illness appropriately enough titled "Prostate". This study in itself completely disproves the "testosterone is bad for you" theory.

* At the Karolinska Institute in Sweden20 another landmark study was done but this time with 2,400! men. The doctors found men with prostate cancer generally had lower testosterone levels than healthy men. Yet today doctors are still cutting off men's testicles and giving them toxic drugs to stop their testosterone production knowing this treatment never works.

* At the University of Southern California in Los Angeles21 doctors studied 1,127 aged men from four distinct racial groups. They found the Asian men with the highest testosterone levels had the lowest levels of prostate illness while Caucasians with the lowest testosterone levels had the highest rates of BPH and cancer.

* At the Ben May Cancer Research Institute22 in Chicago some very brilliant doctors studied human androgen dependent cancer cells in vitro and found that testosterone actually prevented tumor growth. They said androgen deprivation is clearly wrong and we should be studying androgen supplementation for treatment. Doctors like these are going to be responsible for putting reality into medicine instead of the current insanity of stopping testosterone production.

* And yet another landmark study was done at the University of Utah in Salt Lake23 where doctors found the lower the testosterone level in men the larger the prostate volume as men age. Men with higher than normal testosterone levels did not suffer more BPH.

* To show the value of testosterone supplementation generally researchers at the University of New Orleans24 found that 62 aged men given testosterone supplements had increased sexual interest, more sexual arousal, and better sexual enjoyment as well as improved mood. Studies are going to show more and more that men over 50 who retain youthful testosterone levels are going to be healthier and live longer and better lives.

* At the University Medical Center in Norway25 239 men were tested for serum testosterone levels and they discovered higher levels had no relation at all to BPH or cancer of the prostate.

* It is never talked about but it is important to raise androstenedione levels per se as well as testosterone. At Gumna University in Japan 26 androstenedione was found to be a strong 5-alpha reductase inhibitor.

* At Leeds University in England5 human prostate tissue with BPH was found to be deficient in androstenedione.

* At the University of Edinburgh in Scotland27 doctors demonstrated androstenedione was a powerful inhibitor of 5-alpha reductase activity in the human prostate and had clinical therapeutic potential.

* At the University of Rochester in New York28 doctors found an analog of androstenedione called 5-androstenediol (commonly sold over-the-counter) had potential anti-cancer activity in human prostate cells. They concluded that the current theory of androgen blockage needs to be changed.

 

1. J. Urol. 99 (1968) p. 788-92 2. Gerontol. 14 (1968) p. 133-41 3. J. Lab. Clin. Med. 76 (1970) p. 530-6 4. J. Ster. Bio. 6 (1975), p. 1373-9 5. J. Endoc. 69 (1976) p. 15P 6. Prog. Clin. Biol. Res. 6 (1975) p. 143-58 7. J. Endoc. 71 (1976) p. 99-107 8. Probl. Endokrinol. 23 (1977) p. 111-4 9. Cancer Res. 38 (1978) p. 4126-34 10. Experientia 35 (1979) p. 844-5 11. J. Endoc. 83 (1979) p. 31P 12. Vestn. Akad. Med. Nauk USSR 3 (1980) p. 72-7 13. Klin. Exper. Urol. 4 (1982) p. 1930 14. J. Ster. Bio. 22 (1985) p. 521-8 15. Rocz. Akad. Med. Supl. 42 (1984) p. 177 16. Rev. Esp. Fisiol. 46 (1990) p. 63-8 17. Rev. Esp. Fisiol. 47 (1991) p. 161-6 18. Zhonghua Yixue Zazhi 73 (1993) p. 489-90 19. Prostate 27 (1995) p. 25-31 20. Brit. J. Urol. 77 (1996) p. 433-40 21. Cancer Epidem. Bio. Prev. 4 (1995) p. 735-41 22. Proc. Nat. Acad. Sci. 93 (1996) p. 11802-7 23. J. Clin. Endoc. Metab. 82 (1997) p. 571-5 24. Hormone Behav. 31 (1997) p. 110-19 25. Cancer Epidem. Bio. Prev. 6 1997) p. 967-9 26. Endoc. Japan 19 (1972) p. 97-106 27. Steroids 52 (1988) p. 237-47 28. Proc. Nat. Acad. Sci. 95 (1998) p. 11083-8

 

Hair loss and Serum Testosterone

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  • Senior Member

i concur with that swimmy

 

many people complaining of bad sides due to finest use come on line with blood results looking for help and the most common problem seen causing all the bad sides is high oestrogens!

 

which in the end suppressess natural test production which leaves men prone to breast development,test shut down and high amounts of oestrogen!

 

finest will increase the over all free amount of testosterone on offer in the body initialy by decreasing its conversion to DHT...... oestrogen will then go unchecked by not being opposed by the androgen DHT which as we all know is much stronger than test.......... excess oestrogen will then turn off natural test production and leave the male feeling like s**t..... as in the long term finest will lower free testosterone as it will be surpressed by the excess oestrogens.

 

the most common things to use to recreate homestasis after finest knocks it out of line is as mentioned in your study ADEX (arimidex) which decreases oetsrogen then CLOMID which increases Follicle Stimulating Hormone and Lutanising Hormone which results in increased testicle activity to reproduce testosterone levels again!

 

oestrogen results in belly fat deposits in men which then become established and hard to shift and these them selves also produce more ostrogen!

 

so a yearly blood test whilst on finest or dutas to check test levels and oestrogen will go along way to preventing the long term sides mentioned on propecia help web site as in my opinion they are suffering a HPTA inbalance disrupted homeostasis and shut down of the testicals similar to body builders as even though bodybuilders take steroids which is testosterone the shut down of the hormonal endocrine system you hear which gives steroid users ED erectile disfunction is due ot he suppressive nature of oestrogen!!!!!

 

its exactly the same as with finest but with different causes ie one finest and dutas the other steroids the effects in terms of shut down and oestrogen effects is the same!!!!

 

controlling oestrogen will relieve many long term sides of finest how ever always get bloods down!

 

if your oestrogen is to high take adex for a week or 2 at .5mg every other day

if your test production has been surpressed and you have now have low total testosterone take clomid to stimulate production..... for 3 weeks

 

these simple measures will bring oestrogen to normal levels increase test to normal levels and you still have protection against balding and dht from the finest........

 

once oestrogen and test is normal again.... many sides such as breast development depression mood swings dry skin and ED should be much improved also that stubborn belly fat which aids oestrogen will be easier lost!

 

:)

 

 

you coul argue that what i stated above is wrong and will not help finest sides. my advise to you is if you are suffering from sides of long term finest use gets blood done and post results. if oestrogen is high take adex for a week or 2 only and i can guarantee you will feel much better!

 

NEVER TAKE MEDS WITH OUT DRS GUIDANCE AND ONLY AFTER BLOOD TESTS CONFIRM HIGH OESTROGEN BECAUSE IF YOU LOWER IT TO MUCH THIS IS BAD AND WILL RESULT IN ERECTILE DISFUNCTION JUST AS HIGH OESTROGEN DOES ALSO

 

i actually went on propecia help and advised this but they where all to scared to do anythin about the sides instead they just moan on an on but wont do anything about it? another guy how ever on another forum did take the advice and is feeling alot better and his bloods supported the treatment and improvements so it works

 

its similar to post cycle therapy for steroid use google it and read how it gets you back to normal hormonal wise its basically using this concept to restore the internal levels of hormones to normal after finest has knocked it out of wak

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  • Senior Member

also the bit on TRT testosterone therapy was intresting to me because... this means steroid use as TRT is steroids mostly test sust and again another subject i know quite abit about!

 

NO TEST SUPPLEMENTS SHOULD EVER BE TAKEN BEFORE YOU HAVE TRIED UPREGULATING YOUR OWN NATURAL SUPPLY OF TEST VIA POST CYCLE THERAPY AS TRT IS FOR LIFE AS IT WILL TURN YOUR BALLS OFF FOR GOOD UNLESS YOU MANAGE IT CORRECTLY

 

TRT SHOULD ONLY BE CONSIDERED AS A LAST OPTION FOR MEN MOSTLY OVER 50 AND THOSE WITH LOW TEST LEVELS RESULTING IN BAD SIDES

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  • 2 years later...

Depleting amount of testosterone is often the reason for men being overweight and having flabby muscles and feeling dull and unenergetic. Raising testosterone through diet, exercise, or nutritional supplements is often a great way to get back your strength and stamina

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