rj11

3 hours ago, arthurSam said:

Dutasteride and finasteride was both from parati but it was the same composition as xyon

Would you consider trying the 0.1% or 0.5% Dutasteride from parati pharmacia? How did you get a prescription?  

6 hours ago, arthurSam said:

Hello,

I am 47yo

I got a HT last year and got a shock loss but my hair regrowed later. After that I was a lttle hair loss on shower every day (10-15 hairs).

So for stabilization, I tried topical finasteride 3x/week 0.025% 1ml with alcool. My hair loss stopped but I got sides 4-5 months later. So I needed to stop it.

Then, I tried with trichosol but same thing.

Then, I tried with liposomal + sicicone (Xyon gel bought at parati pharmacia) with 2% but same thing.

Then I tried Xyon Dutasteride at 1% but same things.

I tried also oral minox 1mg/day but got sides (heart and renal problems - saw after a blood test of renal filtration rate wich has diminished). So I stopped oral minox and no problems anymore then (my renal filtration rate is now normal).

Now I am on fluridil + cosmerna since 2,5 months (with topical minox 5% at morning too from a while now) and it works great (no hair loss anymore on shower). I got just little side (no morning wood) for few day (1 or 2) after the day of application of CosmeRNA.

I take vitamins too + zinc.

It seems I am very responsive to sides from topical medication, perhaps because I got a atopic skin.

Was the 2% liposomal + sicicone from parati pharmacia Dutasteride or Finasteride just to confirm?

The Xyon Dutasteride 1% was directly from Xyon or from parati pharmacia also?

14 minutes ago, Follicle1984 said:

I'm guessing no one in the UK has bought and received this given the lack of response?

Anyone know when it will be available on Amazon UK?

47 minutes ago, 4Godot said:

There seems to be a lot invested in this slow release mechanism for the gels, so much so that people suggest you should be able to tolerate much higher doses of Dut/Fin because of it. I guess a lot depends on how much you buy into that logic, and especially the concept that dutasteride's molecular weight seriously limits it's systemic impact

Do you have a link for ordering from farmacia parati?

 

Thanks!

You need to email them, I just got an email reply back from them.   

On 4/13/2023 at 11:33 AM, Follicle1984 said:

In all honesty I can't see why you would need to take topical dutasteride more than once a week at most. It's half life is so long. I beleive once it binds to the 5AR enzyme it does not let go, and the time to recover 5AR enzyme levels is reportedly quite long (like a 30 day "reverse half life" to get back 50% 5AR in the tissues...or around those figures). Dutasteride mesotherapy is only given at a dose of 0.1mg and sometimes only monthly or even 3 monthly. So presumably even if 0.1mg gets to where it needs to via any topical route, I can see no good reason it should be used so frequently. 

New to the Forum. Have you possibly tried/looked at LIPODUT - Fue Clinic or topical dutasteride from Farmacia Parati? Also waiting to see if Xyon becomes available in the UK.