I cannot use avodart or proscar because of sexual problems. I tried it many times. I actually was on avodart the day it came out because of the research that was done, but i can not take any oral dht blockers, and to a certain degree my sex drive never came back the way it use to be. so, for me propecia,nizoral, and prayer. I have experience with chemistry and would be willing to make a topical solution out of the oral dht blockers, but I do not know what the success has been on that. And why has the pharmaceutical companies made one yet? I have used every other snake oil substance that comes out too, about once a month a see a info ad and I buy it. For those who had success with other topical substance please do tell. thank you norwood friends