JohnBob

1 hour ago, Shifty said:

Whats the over/under I get brain cancer? And, is it the good brain cancer or the bad brain cancer? 

It has proven to be safe in animals and Tsuji has regulatory authorization to start clinal trials. The consensus is that the worst that can happen is that the cloned hair cells start to get undifferentiated in scalp and become normal skin and the hair disappears. 

That's why it was a breakthrough that Tsuji managed to get the cloned hairs to cycle at least 3 times according to their announcement from yesterday.

55 minutes ago, nicoandgello said:

If you're a human being finasteride will work for you 100% of the time. Please show me a single example of a person that uses finasteride/dutasteride that PSA level didn't lower. We can regrow most hair right now with simple usage of meds. You don't know what you are talking about. Current medicine can cure baldness right now, just not exactly with good sexual side effect profile.

A single example? Most people don't get results with fina. Do you think, for example, Gatsby never tried fina or almost every treatment available in the book? Those show cases you are seeing on the internet are the 0,01% outliers.

I'm not saying this to discourage you, maybe you will be an outlier as well. Also I don't want to derail this thread with this topic. I think we can go back to Tsuji and hair cloning. 

32 minutes ago, nicoandgello said:

It's not the truth. There will never be "cure" to all baldness. Even with gene editing people with alopecia will still be bald. Even with hair cloning people will still continue to bald. In the last 10 years we started using a lot of new treatments. Topical finasteride/dutasteride, oral minoxidil stopped being taboo, doctors are more willing to prescribe low dose AA, hair systems are practically undetectable, FUE is now equal to FUT, new topicals like RU and CB beacame popular, people are now using many diffrent growth promoters other than minoxidil. You don't know what you are talking about, so please stop spreading that boomer logic.

Look man, this "boomer logic" kind of insult doesn't add anything to the debate. Consider stoping it. 

Minox and finasteride doesn't work well for most people and have been around for decades. HTs have evolved but that's pretty much it.

On the other hand, hair cloning, if it works on humans, will be a practical cure.

There are tons of press articles about new revolutionary treatments that promised commercial availability in 5 years and ended up totally folding. Google is your friend if you don't believe in my words. I'm not going to discuss such simple verifiable facts anymore.

1 hour ago, nicoandgello said:

That's just boomer talk, not truth.

He is speaking the truth. Back in 2005 people in the forums were sure the cure was just around the corner. Each and every year the news of a new treatment would pop with the statement that in 5 years it would be commercially available. And then 5 years would pass and nothing would happen. 

But one day this cursed cycle will be broken. 

So just to be clear. Intercytex and ARI were trying to rejuvenate old dormant follicles. 

What Tsuji/Stemson are doing is totally different. They are creating new hairs from scratch. This is more complex but has better chances of succeeding IMO. And they are far ahead too since they already demonstrated the technology works in animals. 

3 hours ago, CosmoKramer said:

This is just a perpetual way to gain steady income in the form of Investor funding then bankruptcy then repeat, for the doctor and his staff, sad to say and hate to sound like a downer, but what the human body creates/replicates on its own is extremely difficult for machines and other artificial sources to replicate even if cells originate from the patient. Gene therapy was supposed to be the cure to many diseases, in fact in some cases it’s been harmful even deadly. Artificial organs were also supposed to be a game changer...hasn’t panned out as the body rejects and so people are still on long organ donor lists. I would love to be proven wrong in 3-5-10 years but I highly doubt it.
 

Progress in biotech takes time, we are talking decades here.

It took literarily 20+ years and BILLIONS in funding before the mRNA technology finally had its first use case with the covid vaccines. 

1 hour ago, Gatsby said:

Any announcement has always been this. 'In five years we will have a cure.' I've literally heard this 'every five years' for the past 35 years! Lol!

Lol ain't that the truth!

So in a nutshell Tsuji demonstrated that they successfully cloned hair in mice that apparently even cycled normally. This is a first. Intercytex or ARI didn't even come remotely close to that. 

The challenge now is to do clinical trials see if the findings translate to human hair. Huge challenge and Melvin is right to be skeptical but steps are definitely happening in the right direction. 

We also have Stemson, a well structured company that had similar results in mice with a different cloning approach and now are about to perfect the procedure in pigs to prepare for human trials too. 

17 minutes ago, Melvin-Moderator said:

It hasn’t, it’s the same story, different company. Promising phase I goes to Phase II, dies before phase III. 

I'll have to disagree on that Melvin. Intercytex and ARI never showed anything with substance to back their claims. Tsuji, on the other hand, have scientific studies published and even a paper on Nature demonstrating the successful creation of a cloned hair in mice. Same for Stemson. 

You may say cloned hairs on mice are a far cry from the cure and I agree, but we now have a working proof of concept of hair cloning. Its an advance that we didn't have before, so I would say the hair cloning field is indeed progressing (albeit not in the speed we want). 

9 minutes ago, Melvin-Moderator said:

We’re far from this future. This has happened at least three times before, we actually visited intercytex in England, they were all the hype, they went bankrupt too and the results ended up being a bust.

14 years ago lol almost the exact same thread. @BeHappy still here too. 

Damn, 14 years ago. I will be damned if this field didn't evolve anything since then. 

42 minutes ago, Melvin-Moderator said:

Dr. Tsuji claimed this would be ready by 2020, hence the website hairlosscure 2020 name lol. The previous company organ technologies went bankrupt, looks like he’s found another company. Don’t hold your breath, expect another fall out.

Another fall out can happen but I expect someone or some company will eventually get it right. I think that path is the future of the hair transplant industry

36 minutes ago, TommyLucchese said:

If it happens, does that make transplants nigh on perfect and viable for everyone....rather than replacing HTs?

Yes. Both Tsuji's and Stemson's versions of hair cloning will involve the the implantation of the cloned cells onto the scalp. Only instead of transplanting a hair graft, it will be used a hair germ with the cloned cells so to speak. Each hair germ will result in one new hair follicle. 

Both companies/docs said they would like the current HT surgeons doing it, as it will demand similar skills of a traditional hair transplant (minus the donor extraction part). 

Stemson even has two HT doctors from SoCal (where they are based) in their board of advisors:

https://stemsontx.com/team/

This is the future of HTs folks. 

Thanks for https://www.hairlosscure2020.com for noticing and reporting it first!

Do you guys think this finally is going to be it? Depending on the news - say they already started clinical trials and show a cloned hair implanted and growing on a human being -  the hair loss world will be torn upside down! Imagine the best HT surgeons being able to implant an unlimited amount of hair follicles, not even the sky will be a limit!

@Melvin-Moderator is a post op from your last procedure? Is the dark part part of you scalp (front) thicker than the rest? Did you plan to implant more grafts per cm2 there compared to the rest of your scalp?

14 minutes ago, mustang said:

I have never seen such beautiful and clean work

This man us truly on another level.

How do you think he compares with Dr. Couto (since you had surgery with him)?

3 hours ago, Alterego said:

Hi all,

I never had an hair transplant. I'm losing hair on back of my head, under the nape. It is depressing and frustrating. I feel like a Norwood 8 or even 9. In addition to being totally bald, I'm losing the hair I still had. Anything I can do to prevent this?

Thanks

As others have said, it looks like you don't have enough healthy hairs in your head for a traditional HT using scalp hair. 

BUT, don't throw the towel yet. I have seen men in a similar situation as you getting their whole head covered again with BHT. But there is a catch: they had extremely good chest hair (and maybe back hair too). How is your hair in those areas?

On 1/8/2021 at 8:39 PM, gillenator said:

No, never spoke to her again however I did see her several weeks later in the same club that I met her in...but she just looked at me and walked the other way...actually, she was a pretty decent gal and not the type that would humiliate me.

I actually looked pretty good in my system but once she knew...that was it...we just went our separate ways and that was fine with me...obviously she felt the same way...HA!

haha I wonder if she became paranoid and started to visually inspect the scalps of the guys she dated after you - even trying pulling a chunck of their hairs to see if they are really attached to their scalps!

1 hour ago, DrTBarghouthi said:

I dont personally know Dr. Zarev but he seems to be delivering impressive results based on what is posted. Nonetheless, in fairness to other doctors around, I haven’t seen anything extremely revolutionary in the video. It takes many doctors 1.5-2 hours to shave, discuss and draw and plan the procedure. Our extractions rarely start before 10 while the patient is in by 8 am. Many doctors including myself give the anesthesia and even shave and take photos ourselves. I think planning is an extremely important step and anyone working in a surgical field should be aware of that. It just feels right to get into your car and make sure your seat and mirrors are adjusted before driving. 
From a technical point of view I did notice some things that I would personally disagree with. The first is a “single” foreceps extraction which can work in some cases but to me using two forceps is always less forceful on the grafts. The other point is the lack of magnification during extraction and during the techs sorting the grafts. I think magnification is extremely important and I just wonder why this is not used- for both quality control and also not to strain the operators vision. 

Doctor, thank you for your analysis and feedback! Being able to read the qualified opinion of other physicians participating in this forum is such a privilege. 

Indeed nothing revolutionary is shown in that video just a doctor that appears to be very diligent. 

In the screenshot Melvin posted of Dr. Zarev's Instagram he was asked about the lack of magnifying glasses and he answered that he doesn't need them, but I find that strange too. 

Regarding the double forceps, maybe that's a suggestion that could be forwarded to him (in the right context, of course).

One thing that is worth being noted is that he may be using device totally different from the standards to "lose" de FUs on the scalp before pulling them out. He is blurring the video as to not allow us to see what kind of device he is using but if I would guess he is using some suction for that since that is in line with "AVA technique" he claims to be using. 

So he says he uses a vacuum assisted technique that he developed to harvest the donor area, but we now also know that he uses tweezers to pull the hairs out. So does it mean he uses vacuum as a replacement for the punch part? I'm confused. 

Also, did you guys notice the blurred out the device he is using to do the extraction "punches" (or whatever thing he is doing)?

11 minutes ago, Melvin-Moderator said:

I think the whole DHI has been hyped up to the point of being a selling point. Using forceps has been around for decades. Some of the best clinics use this technique, hasson and wong does for example. But again, dissecting a video, it’s hard to say these techniques are revolutionary.

But you don’t have to reinvent the wheel to get good results, which is what I’ve been saying, and even Dr. Zarev said what I said earlier in this thread, which is a good sign. 

Another surgeon may have played on the “god” status he’s been receiving, instead of being truthful. Glad to see he told the truth. 

Dr. Zarev never came across as a "salesman" doctor or caring too much about marketing (at least in my opinion). If you look at this YT videos they are pretty dull, no musics or special effects, but the cases he presents are extremely well documented. 

He does even the anesthesia injections himself, and which doesn't seem so smart in a purely business point of view but it goes to show where his priorities are.

24 minutes ago, Melvin-Moderator said:

I don’t think there’s anything else to say.

 

This is very anti climax Melvin, I understand someone needs to act like an adult around us kids in this thread but please comment about the video too lol

He is using tweezers like the other doctors so he is not using vacuum to pull out the grafts as we thought

@Melvin-Moderator what do you think about the methods he showed and how he conducted the operation? Do you think it is on par with the other world class HT surgeons?

9 minutes ago, Captain Haddock said:

This was interesting to watch.

Also, a very professional doctor, spends two hours planning the procedure and takes all the shots himself. Very nice to see. And there's a machine that counts the grafts! Wow. That is news to me. 

Man seems like he had the results and the science to back it. I'm afraid he will become a Couto soon and the waiting lines will become endless!

Zarev just posted in his IG part of his presentations at the GHLS 2020.

https://www.instagram.com/p/CJ4YD1LDCGR/?igshid=16s9iru9c91w3

Very interesting and gives us a more detailed look on how he operates, definitely worth viewing it!

He is very hands on and meticulous, and does all the stages of the operation himself. Says it takes 2 hours just for the planning - is it normal?