CureSeeker

Yes, dissolved into 1X PBS solution via ultrasonic cleaner, and I used 30 Gauge 4mm mesotherapy needles and injected them at full depth.

Thanks, and no I'm not on any medication. I've done microneedling in the past, even deep microneedling, with no results and I consider that a good enough control.

If anyone's curious, I designed and printed that syringe dispenser to meter out specific quantities per press of the plunger: https://www.thingiverse.com/thing:5400166

Yes, I started it on Sunday, for a 2cm-diameter section on my scalp. 2mg/mL concentration, 0.7mg/cm² dosage, and then manually microneedled with a 12-pin cartridge. I did it manually so I could press the needles in to their deepest depth, and apply some rotational mechanical force. I also applied some benzocaine-ethanol solution to take the edge off any pain.

Just microneedling

I've tried microneedling in the past without success, in both areas.

There are a lot of people in this thread claiming to know how verteporfin treatment will work and even how the potential follicles will behave, despite it never being tested. If it hasn't been tested, you do not know. That's literally why we do tests. At any rate, I've procured some verteporfin and will be starting my own test on myself this week (deep microneedling of the thinning area).

On the topic of microneedling+verteporfin, here's a case where it regrew hair

Do you know what solvent he used? Like DMSO?

Does anyone know the concentration/molality of the verteporfin solution that Dr. Barghouthi was using?

This is what I meant by people not being able to get verteporfin. It sounded like you were saying there were ways to get ahold of some without a doctor's prescription. If so, I'd like to look into that.

Can you DM me details about the discord/telegram? The site won't let me DM you, probably because my account's newish.

I'm sure many people would be happy to test it at home themselves. The problem is people can't get verteporfin.

Yes, this exactly. We're in uncharted territory, so none of us really know. We can speculate on plausible results though. Not only have we not tested verteporfin much, we haven't even done tests with de novo follicle generation in human skin, because no therapy has successfully done that yet. Assuming verteporfin can, we don't know how those brand new follicles would behave in comparison to old, degraded follicles. It could be that any single follicle needs a decade of DHT exposure before it starts to miniaturize. That would be awesome.

Again, if verteporfin causes new follicles to be produced rather than rejuvenating old follicles, then the state of any existing follicles is less relevant. Also, the difference between follicles in the crown vs in the donor region is not their DNA. It wouldn't take DNA mutation to make the follicles resistant (I'm NOT saying verteporfin would do this, I'm just addressing your remark about mutation). All cells in the body, aside from things like gametes, have identical DNA. There can be some very small variations due to sporadic mutations or telomeres but those are negligible. The differences between those two hair follicle cells is in their states, such as their epigenetic configurations (i.e. DNA methylation, histone modifications), protein markings, etc, rather than the DNA itself. It's also how stem cells are differentiated and dedifferentiated.