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Gokul Krishnan

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Posts posted by Gokul Krishnan

  1. 33 minutes ago, DrTBarghouthi said:

    Hi guys,

    Apologies for the silence. We just finished an FUE case and injected 4 different doses of Verteporfin in specific areas of the mid scalp in order to be able to go back to the exact spots. We used SMP around the areas extracted but also measured precisely the location of each of the spots. The dosages used were: 0.4 mg, 0.6, 0.8 and 1 mg. Photos were taken using the Tricholab system. Will update and share shortly. Happy to hear about all the updates from the community and @Melvin- Admin

    Mid scalp ? 🤔

  2. I am 31 M, NW2 level balding. I had 2 hairline lowering procedures (1250 + 750). I still feel the hairline in the front ~0.75 cm is sparse and want to fill it. It should take 250-300 grafts.

    Now I am worried that all the soft singles have already been used in the past 2 procedures. Is my concern valid?

    Can we split 2 hair grafts to 2 single hair grafts ? If yes, will it match the real singles texture ?

     

    My Donor:

    image.thumb.jpeg.538274a13130a823267ddbe958987da4.jpeg

     

  3. I had a HT recently in hairline. Bumped my head (not too hard but significant) on 2nd day (~50 hours). Did not see any blood. I checked with my doctor, she said not to worry after examination. But the line from below article, scares me.  

    "Even if you don’t notice any bleeding, trauma can mean permanent damage to the grafts."

    https://www.longevitahairtransplant.com/guides/bumped-head-after-hair-transplant/#Bumped_Head_After_The_Hair_Transplant_Are_the_Grafts_Okay

    Did I lose my grafts? Is losing grafts always indicated by blood?

  4. 7 hours ago, trends said:

    For the first 1 or 2 you will feel slight sting, then you start getting used to and with the numbness around you don't feel anything. I was concerned about the pain too, but I would say the whole thing was painless. Also a trick to not feel the 1st pricks is to the hold your breath for 5sec. 

    Holding the breath ..Hmm.. did not expect this..Here I am trying to pinch myself to test your trick 😜

  5. 18 hours ago, TrialAcc said:

    You should look into rescheduling it. It looks like India could be facing some large scale systemic failures through their medical infrastructure and as I'm assuming you're a foreigner you probably don't want to risk getting stuck there or worse getting actually sick and not having medical treatment available to you after already undergoing a medical procedure.  

    This is also a guess, but I'm assuming covid would be very bad for new hair growth after a transplant. Covid is an inflammatory virus that harms the body through androgen receptors (among other things). Many people who have had covid have suffered hairloss in the resulting months.  

    I am an Indian but from the Southern Part. Yes. I have rescheduled because of the current situation. I did not know Covid resulted in Hairloss. Thanks for the Info.

  6. Given the current COVID crisis in Delhi,Haryana, I am really worried and stressed. 

    I am extremely worried about the negative scenario (less probable yet..) where I am tested Covid Positive after my HT and trapped in Delhi/Gurgaon.

    Any suggestions from Indians in the forum regarding that?

    https://timesofindia.indiatimes.com/city/delhi/live-news-lockdown-in-delhi-night-curfew-covid-cases-noida-gurgaon-ghaziabad-temperature-pollution-21-april-2021/liveblog/82166929.cms 

    Also I am worried about implications of Covid infection on my HT. Can someone explain?

     

     

  7. 1 minute ago, Dr. Suhail Khokhar said:

    I said systemic side effects, I didn't say NO side effects. That's a big difference. The only side effect I've seen is irritation/itching due to contact dermatitis. 

    Yes. I got your point. I am skeptical that it has no systemic side effect. Not an expert, but my thoughts are when used for long periods some amount of finasteride will get accumulated in system and it will take months or years for systemic side effects to show.

  8. I would like to present a crazy idea.

    History: I am a NW2 aged 28 with good crown and mild scalp density. Family history is such that no major baldness NW4 (with low density) at age 60. My prediction of my future hair loss is very slow receding of hairline to NW4(with low density) about the age 50. 

    Idea: To use crown and midscalp grafts as donors for hairline lowering.

    Reason: If donors are taken from safe donor zone, then after 10 years I might need another transplant since hairline is permanent and the native hairs behind the hairline will fall and it will look really bad. So to avoid this scenario, can we implant grafts from crown & midscalp zone which will fall off with native hair and baldness progression looks normal for a 40/45 year old. *I DONT WANT TO TAKE FINASTERIDE OR MINOXIDIL*

    Expectation: I would like to lower my hairline by 1 cm which could take approximately 1200 grafts.I want to enjoy the new lowered hairline for approximately 10 years. After that I don't care.

     

    I feel this is a crazy idea. Don't know why.. But can anyone say why this is a bad idea?

     

     

  9. 20 hours ago, asterix0 said:

    So, I have found one recent study published just a month ago showing some skepticism:

    https://www.jcasonline.com/article.asp?issn=0974-2077;year=2020;volume=13;issue=4;spage=292;epage=297;aulast=Kumaresan

    Abstract    

    Background: The longevity of the grafted hair follicles is still debated and there are limited literature available on this topic. Aim: To assess the longevity of transplanted hairs after follicular unit transfer (FUT). Materials and Methods: A total of 112 patients who had undergone FUT were included in the study and their results at the end of 4 years were compared with the 1 year post surgery results by standardized images. The reduction in the density of the grafted hair follicles was graded by a blinded observer in a grading scale. Results: Among 112 subjects 50.89% had grade 4, 46.42% had grade 5, 2.67% had grade 6 alopecia respectfully. The 4 year follow up grading of hair loss showed moderate reduction in transplanted hair density in 55.35%, slightly reduced density in 27.67% greatly reduced in 8.03% and no change in the density in 8.92% subjects. Conclusion: The hair grafts transplanted may not last permanently for all the subjects. Recipient site influence might affect the growth and long-term survival of the transplanted hairs.

     

    Here are some more examples:

    https://pubmed.ncbi.nlm.nih.gov/16931898/

    Abstract

    Pathogenetic mechanisms in androgenetic alopecia are not yet fully understood; however, it is commonly accepted that androgens like testosterone (T) and 5alpha-dihydrotestosterone (5alpha-DHT) inhibit hair follicle activity with early induction of the catagen. Thus, we investigated the influence of T and 5alpha-DHT on proliferation, cell death and bcl-2/bax expression in cultured dermal papilla cells (DPC) from nonbalding scalp regions of healthy volunteers. T and 5alpha-DHT induced apoptosis in DPC in a dose-dependent and time-related manner; in addition a necrotic effect due to T at 10(-5) M was found. Interestingly, bcl-2 protein expression was decreased in T- and 5alpha-DHT-treated cells, leading to an increase in the bax/bcl-2 ratio. In addition, T and 5alpha-DHT induced proteolytic cleavage of caspase 8 and inhibited proliferation of DPC at 10(-5) M. High concentrations of T and 5alpha-DHT were needed to induce apoptotic effects in DPC. These data suggest that DPC from nonbalding scalp regions do have the capacity to undergo apoptosis, but need a high androgen stimulus. The present study provides an interesting new pathogenetic approach in androgenetic alopeci

    wow man.. appreciate your effort.

    • Like 2
  10. On 2/11/2021 at 5:52 AM, Style22 said:

    Dr. Khokhar,

    I see you post this as if it were fact all the time on this site... Every single Topical fin study I have seen shows Systemic reduction of dht. Similar to if not greater than oral fin. Am I missing something? Is there a topical fin compound that has any sort of data to back these claims? Not doubting your clinical experience but the data would suggest otherwise stating that there is no systemic absorption of topical fin. I myself struggle with Fin sides so I am certainly looking into these topical options heavily right now.

    yes. I am really skeptical when someone says topical finasteride has NO side effects. Need more data to be conclusive.

  11. I am a NW2 and aged 28. No sign of rapid baldness or hair loss. I have very slow progression of hair loss. I am planning for HT to lower my hairline little bit. I DONT WANT TO TAKE FINASTERIDE after transplant. My queries are..

    1. Will all the transplanted hairs grow even if don't take finasteride after surgery?
    2. Does transplanted hair fall after sometime? or is it permanent? I have read the transplant hair also undergoes miniaturisation and eventually fall off. I comfortable being bald in my late 40s. But I am skeptical about whether my hairline will look bad if only surrounding native hairs fall out.
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