Giddy

1 hour ago, DrTBarghouthi said:

Hi guys. Here are the updated photos. As you can see, there is scarring in both control and test areas. The test area is a bit more pigmented and I think that the scarring is slightly better. Maybe it needs more time or a dose adjustment. Nonetheless, the tiny hairs in the test areas across the 3 dosages is becoming more of an obvious feature in comparison to control areas. 
 

 

 

Definetly a chance it needs more time. In the presentation of pig study with verteporfin they found that the elasticity increased from week 12 till week 16, when they ended the study. So they believe regenerative remodeling started from week 12. 

Also the FAKI study from 2022 stated that there was an early anti inflammatory effekt and a late regenerative effekt. So the verteporfin wounds could have potential to remodel still. And if the hairs are really regenerated then most likely the skin should be regenerating too.

Sources:

https://surgery.stanford.edu/content/dam/sm/surgery/documents/HolmanLectureBooklet_2022 FINAL.pdf

https://www.science.org/doi/10.1126/scitranslmed.abj9152
 

2 hours ago, DrTBarghouthi said:

It wouldn’t be long. If it’s proving to be beneficial in either wound appearance and/or some degree of hair improvement or regrowth, then I don’t see any reason not to offer it as part of the procedure. It would be similar to practices that add PRP or use specific post op dressings etc. It will be something that we just incorporate into the procedure for those who want- despite it being off-label.

You dont happend to be in touch with any clinic in EU that could use verteporfin or do surgery yourself with verteporfin in EU? If not im happy to travel to Jordan in the future too! And I am grateful for your efforts.

Im also a bit confused about the scar tissue. Like is there still an observable difference between T and C in terms of scar tissue structure, development etc.? Feel like it was easier to spot the difference between T and C in previous follow-ups.