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Thisisnotatest333

how Finestiride actually should ve been tested

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The major problem of making studies for such a medication is that people know the possible side effects. I can almost guarantee that 99% of people that got lower libido, got it because they got depressed over possible side effects. Someone should pay balding people to take fin for some time and the examine them. I know this might not be the ethical solution but if people take money  whats the worst that can happen? Those effects were mostly reversable.

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I actually think it should have been officially released as a topical from the start, as I’ve recently read that topical Finasteride gives the same results as oral with out systemic side effects if someone is susceptible...and topical inhibits more scalp DHT than the pill, from one article I read covering the studies.

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@CosmoKramer I've been advised to switch to a topical finasteride / minoxidil mix, replacing finasteride pills.  Do you apply topical finasteride while microneedling?   I wonder if I should stop microneedling while applying topical finasteride. 

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On 11/12/2019 at 5:30 PM, Thisisnotatest333 said:

What are the well known topical fin products? (if any even exist)

None official that I know of, only ones that people have their local compounding pharmacy create one or they make a mix themselves with crushed Proscar/propecia pills.

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2 hours ago, js1283 said:

@CosmoKramer I've been advised to switch to a topical finasteride / minoxidil mix, replacing finasteride pills.  Do you apply topical finasteride while microneedling?   I wonder if I should stop microneedling while applying topical finasteride. 

I have not yet tried applying Finasteride topically but am planning to do so soon, I have the pills and purchased some propylene glycol and ethyl alcohol to use as carriers, it’s close to the same ingredient as in Minoxidil solution just without the Minoxidil drug, I will be testing to see how much progress I get with this mix & microneedling without Minoxidil.

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Mine is being made at a pharamacy.  My only concern is the amount of absorption of finasteride into the bloodstream. Since microneedling dramatically increases the absorption of topical solutions into the bloodstream, I wonder if this would result in the topically applied finasteride becoming too potent and unsafe.  

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1 hour ago, js1283 said:

Mine is being made at a pharamacy.  My only concern is the amount of absorption of finasteride into the bloodstream. Since microneedling dramatically increases the absorption of topical solutions into the bloodstream, I wonder if this would result in the topically applied finasteride becoming too potent and unsafe.  

Then you should wait at least 12-24hours after microneedling before you apply it if you have systemic absorption concerns.

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0.25% topical finasteride is probably more effective though.  

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1 hour ago, js1283 said:

According to this trial, switching from 1mg finasteride pills to 0.1% topical finasteride led to a slight hair loss: 
http://www.idoj.in/article.asp?issn=2229-5178;year=2015;volume=6;issue=1;spage=17;epage=20;aulast=Chandrashekar

Interesting study...I do like the end point they state that switching to topical Finasteride could help keep the progress gained from having used oral Finasteride and then stopping its use but continuing with topical.

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1 hour ago, js1283 said:

0.25% topical finasteride is probably more effective though.  

Yeah, I’m planning to make a 0.30-0.50% topical mix in a month or two since I’ll likely use more than 1mL each application.

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On 11/30/2019 at 10:19 PM, CosmoKramer said:

Interesting study...I do like the end point they state that switching to topical Finasteride could help keep the progress gained from having used oral Finasteride and then stopping its use but continuing with topical.

I think they said the hair loss stabilized after switching to topical from oral, but only after some loss. i.e., there was some net loss immediately after switching to 0.1% topical. 

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54 minutes ago, js1283 said:

I think they said the hair loss stabilized after switching to topical from oral, but only after some loss. i.e., there was some net loss immediately after switching to 0.1% topical. 

Interesting. Maybe if it was more than the 0.1% they used that there would less net shed loss hmm..

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On 11/4/2019 at 11:08 PM, Thisisnotatest333 said:

The major problem of making studies for such a medication is that people know the possible side effects. I can almost guarantee that 99% of people that got lower libido, got it because they got depressed over possible side effects. 


Before posting something like this, you should study how scientific research is planned.
Have you ever heard about double blind studies?
You take 2 groups of people.
One take the product and the other take. a placebo.
The people do not know if they are taking the product or placebo.
Then you have some doctors that study the effect. They do not know what people are taking, because sometimes if the doc knows what the patient is taking, this can influence the validity of the statements.
Then you have another group of people that see analyze the conclusions of the docs.

So, imagine you have 3% of people suffering impotence in place group.
You can say that 3% is not real.
If you find 5% of people suffering impotence in fina group, you can say that fina causes impotence in 2% of people taking this drug.
 

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