Senior Member Thisisnotatest333 Posted November 4, 2019 Senior Member Share Posted November 4, 2019 The major problem of making studies for such a medication is that people know the possible side effects. I can almost guarantee that 99% of people that got lower libido, got it because they got depressed over possible side effects. Someone should pay balding people to take fin for some time and the examine them. I know this might not be the ethical solution but if people take money whats the worst that can happen? Those effects were mostly reversable. Link to comment Share on other sites More sharing options...
Senior Member CosmoKramer Posted November 12, 2019 Senior Member Share Posted November 12, 2019 I actually think it should have been officially released as a topical from the start, as I’ve recently read that topical Finasteride gives the same results as oral with out systemic side effects if someone is susceptible...and topical inhibits more scalp DHT than the pill, from one article I read covering the studies. 1 Link to comment Share on other sites More sharing options...
Senior Member Thisisnotatest333 Posted November 12, 2019 Author Senior Member Share Posted November 12, 2019 (edited) What are the well known topical fin products? (if any even exist) Edited November 12, 2019 by Thisisnotatest333 Link to comment Share on other sites More sharing options...
Regular Member js1283 Posted November 21, 2019 Regular Member Share Posted November 21, 2019 @CosmoKramer I've been advised to switch to a topical finasteride / minoxidil mix, replacing finasteride pills. Do you apply topical finasteride while microneedling? I wonder if I should stop microneedling while applying topical finasteride. Link to comment Share on other sites More sharing options...
Senior Member CosmoKramer Posted November 21, 2019 Senior Member Share Posted November 21, 2019 On 11/12/2019 at 5:30 PM, Thisisnotatest333 said: What are the well known topical fin products? (if any even exist) None official that I know of, only ones that people have their local compounding pharmacy create one or they make a mix themselves with crushed Proscar/propecia pills. Link to comment Share on other sites More sharing options...
Senior Member CosmoKramer Posted November 21, 2019 Senior Member Share Posted November 21, 2019 2 hours ago, js1283 said: @CosmoKramer I've been advised to switch to a topical finasteride / minoxidil mix, replacing finasteride pills. Do you apply topical finasteride while microneedling? I wonder if I should stop microneedling while applying topical finasteride. I have not yet tried applying Finasteride topically but am planning to do so soon, I have the pills and purchased some propylene glycol and ethyl alcohol to use as carriers, it’s close to the same ingredient as in Minoxidil solution just without the Minoxidil drug, I will be testing to see how much progress I get with this mix & microneedling without Minoxidil. Link to comment Share on other sites More sharing options...
Regular Member js1283 Posted November 21, 2019 Regular Member Share Posted November 21, 2019 Mine is being made at a pharamacy. My only concern is the amount of absorption of finasteride into the bloodstream. Since microneedling dramatically increases the absorption of topical solutions into the bloodstream, I wonder if this would result in the topically applied finasteride becoming too potent and unsafe. Link to comment Share on other sites More sharing options...
Senior Member CosmoKramer Posted November 21, 2019 Senior Member Share Posted November 21, 2019 1 hour ago, js1283 said: Mine is being made at a pharamacy. My only concern is the amount of absorption of finasteride into the bloodstream. Since microneedling dramatically increases the absorption of topical solutions into the bloodstream, I wonder if this would result in the topically applied finasteride becoming too potent and unsafe. Then you should wait at least 12-24hours after microneedling before you apply it if you have systemic absorption concerns. Link to comment Share on other sites More sharing options...
Regular Member js1283 Posted December 1, 2019 Regular Member Share Posted December 1, 2019 According to this trial, switching from 1mg finasteride pills to 0.1% topical finasteride led to a slight hair loss: http://www.idoj.in/article.asp?issn=2229-5178;year=2015;volume=6;issue=1;spage=17;epage=20;aulast=Chandrashekar 1 Link to comment Share on other sites More sharing options...
Regular Member js1283 Posted December 1, 2019 Regular Member Share Posted December 1, 2019 0.25% topical finasteride is probably more effective though. Link to comment Share on other sites More sharing options...
Senior Member CosmoKramer Posted December 1, 2019 Senior Member Share Posted December 1, 2019 1 hour ago, js1283 said: According to this trial, switching from 1mg finasteride pills to 0.1% topical finasteride led to a slight hair loss: http://www.idoj.in/article.asp?issn=2229-5178;year=2015;volume=6;issue=1;spage=17;epage=20;aulast=Chandrashekar Interesting study...I do like the end point they state that switching to topical Finasteride could help keep the progress gained from having used oral Finasteride and then stopping its use but continuing with topical. Link to comment Share on other sites More sharing options...
Senior Member CosmoKramer Posted December 1, 2019 Senior Member Share Posted December 1, 2019 1 hour ago, js1283 said: 0.25% topical finasteride is probably more effective though. Yeah, I’m planning to make a 0.30-0.50% topical mix in a month or two since I’ll likely use more than 1mL each application. Link to comment Share on other sites More sharing options...
Regular Member js1283 Posted December 8, 2019 Regular Member Share Posted December 8, 2019 On 11/30/2019 at 10:19 PM, CosmoKramer said: Interesting study...I do like the end point they state that switching to topical Finasteride could help keep the progress gained from having used oral Finasteride and then stopping its use but continuing with topical. I think they said the hair loss stabilized after switching to topical from oral, but only after some loss. i.e., there was some net loss immediately after switching to 0.1% topical. Link to comment Share on other sites More sharing options...
Senior Member CosmoKramer Posted December 9, 2019 Senior Member Share Posted December 9, 2019 54 minutes ago, js1283 said: I think they said the hair loss stabilized after switching to topical from oral, but only after some loss. i.e., there was some net loss immediately after switching to 0.1% topical. Interesting. Maybe if it was more than the 0.1% they used that there would less net shed loss hmm.. Link to comment Share on other sites More sharing options...
Senior Member duchaine Posted December 9, 2019 Senior Member Share Posted December 9, 2019 On 11/4/2019 at 11:08 PM, Thisisnotatest333 said: The major problem of making studies for such a medication is that people know the possible side effects. I can almost guarantee that 99% of people that got lower libido, got it because they got depressed over possible side effects. Before posting something like this, you should study how scientific research is planned. Have you ever heard about double blind studies? You take 2 groups of people. One take the product and the other take. a placebo. The people do not know if they are taking the product or placebo. Then you have some doctors that study the effect. They do not know what people are taking, because sometimes if the doc knows what the patient is taking, this can influence the validity of the statements. Then you have another group of people that see analyze the conclusions of the docs. So, imagine you have 3% of people suffering impotence in place group. You can say that 3% is not real. If you find 5% of people suffering impotence in fina group, you can say that fina causes impotence in 2% of people taking this drug. 1 Link to comment Share on other sites More sharing options...
Senior Member Thisisnotatest333 Posted December 16, 2019 Author Senior Member Share Posted December 16, 2019 i think the main reason people get sides from fin is because they didnt get the bloodwork checked before taking the drug. Your test and estrogen levels are very important in this equation Link to comment Share on other sites More sharing options...
Senior Member Betterhair Posted January 3, 2020 Senior Member Share Posted January 3, 2020 People are overdosing which in turn causes side effects probability to increase. 1 mg 3 x's weekly is sufficient Link to comment Share on other sites More sharing options...
DupeDupex Posted March 24, 2020 Share Posted March 24, 2020 (edited) Finasteride (Propecia) has been approved for men with pattern baldness since 1998 with a relatively low side effect profile. Potential side effects include decreased libido and disturbed sexual function, but the majority of research shows that these sexual side effects are reversed when the drug is withdrawn. So if you want to have good hair you have to be ready for this side effect. I have finished the cycle of Finasteride, during it, I was using Comprare viagra generico for potency. Edited March 26, 2020 by DupeDupex Link to comment Share on other sites More sharing options...
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