Jump to content

Gene discovery may lead to new baldness drugs


Guest
 Share

Recommended Posts

LONDON (Reuters) - Researchers have identified a gene linked to hair loss that could lead to new drugs to treat baldness.

 

The gene is responsible for a rare hereditary form of hair loss known as Hypotrichosis simplex, a condition affecting 1 in 200,000 people, in which people begin going bald in childhood, the researchers reported in the journal Nature Genetics.

 

"There is a very good chance of developing a therapy to treat hair loss based on this finding," the study's leader Regina Betz, a researcher at the Institute of Human Genetics, said in a telephone interview on Monday.

 

Currently, Merck and Co's Propecia and Pfizer Inc's Rogaine are drugs sold to stop baldness, but they help people maintain their hair rather than grow new follicles.

 

Using DNA samples from 11 members of a Saudi Arabian family that had inherited the rare condition, the researchers found that a mutation in the P2Y5 gene prevented proteins called growth receptors on hair follicle cells from forming properly.

 

This meant a substance needed to stimulate hair growth could not attach to the defective receptors and may help explain hair loss, the researchers said. The finding could lead to drugs that target these proteins to boost hair growth, they added.

 

"We can now search selectively for related substances that may be used in therapies for hair loss," Ivon von Kugelgen, a researcher who worked on the study at the Institute of Pharmacology and Toxicology in Bonn, said in a statement.

 

"The exciting possibility here is that such medicines will be able to benefit patients suffering from very different types of hair loss."

 

(Reporting by Michael Kahn, Editing by Janet Lawrence)

Link to comment
Share on other sites

  • Regular Member

Thats pretty interesting stuff. Id imagine that gene therapy is way off in the future however and will have all sorts of ethical road blocks to breakthrough before it becomes a reality.Im not talkin from any experience or prior research mind you.

 

What if the treatment went all wrong and instead of gettin new hair we got loads of fingers growing out of our scalp. That would really suck.

Link to comment
Share on other sites

  • 11 months later...
Gene discovery may lead to new baldness drugs

Currently,Cytotec are drugs sold to stop baldness,but they help people maintain their hair rather than grow new follicles

 

(promotional link removed)

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share

×
×
  • Create New...