olmert

I certainly don't think the dut in anagenica has gone systemic in me. I tried finasteride pills and instantly lost all libido. I had to stop. Eventually I tried Anagencia, and my libido stayed high. When I tested my DHT, I found my DHT was much lower with the finasteride pill than with this topical. I feared Anagencia was not penetrating, so I started to microneedle before the Anagenica. Still, no reduction in libido.

Not using Xyon. Using the competitor from Anagenica. It is much cheaper. Libido is great. I don't believe subjective assessments are reliable for whether a topical is growing hair, so I have no idea if it is doing anything. I started micro-needling before using the Anagenica because I skeptical any of it is penetrating. Even with the micro-needling, there is no libido loss, so I have my doubts that any of it is getting inside me.

Pharmaceuticals cost a billion dollars to test in part because you need to test a large population to weed out natural fluctuation. This is why a study of only 10 people isn't much evidence of anything. The study probably means there is a 51% chance topical dutesteride decreases balding, and a 49% chance topical dutesteride does nothing. There is no money to test topical dutesteride with any degree of reliability--to get a figure any higher than 51%. I suppose my own outcome is even less evidence than a 10 person study. I definitely feel, though, that my libido is 10 times higher on topical dutesteride than it was on .2 mg/day of finasteride pills.

The range of results from the study means just about any result will be considered "on par."

@hairman804, @Melvin- Moderator, @asterix0, @DedLifts, it boggles my mind how 90% of people think they can subjectively tell whether Dutersteride worked. It has been studied extensively. 90% of people think they can tell the difference between coke and pepsi, but in blind tests only 10% of people can. https://daily.jstor.org/the-coca-cola-wars-can-anybody-really-tell-the-difference/ My evidence is not subjective. My objective DHT level went from 36 to 46 when I moved from pills to topical.

Studies show people are very bad judges for these things. A better judge is something objective like your DHT count.

I was taking .25 mg/day of Finasteride pills for many years. Then I went off it for 2 weeks and tested my DHT at 36. Then I used topical Dutesteride .1% (strongest one) from http://anagenica.com/ for a month. I tested my DHT at 46. I can tell you one thing. My sex drive was much lower with the .25 mg/day of Finasteride, and was super high when on the topical Dutesteride. Should I conclude the topical Dutesteride doesn't work? If the topical stuff is snake oil, then my DHT should not have gone up, but should have stayed the same. It is also possible there was still some finasteride pills in my system when I tested at 36. I only took 2 weeks off the pill for that test. I know Dr. Bhatti says in a Youtube that he doesn't think topical dutesteride/finasteride works. I'm fearing he is right. Bhatti's warning is two fold. 1. First most stuff you put on skin never penetrates down, so it does nothing. My DHT level makes me think this is the case. 2. Second, if topical dutesteride does penetrate, it might penetrate so well that it hits the blood and is the same as swallowing a pill. So just swallow a cheap pill.

Anagenica's instructions say to start out once a week, and eventually rise to 3 times a week. I was bold and started at 3 times a week. I definitely felt sex effects. So I stopped taking it for 5 days, and the sex effects were gone, I think. I am going to compromise and try twice a week. If I were you, I would risk it and start with 3 times a week. It is true, though, that some people have gotten permanent sex effects from oral finasteride; it continued even after the pills stopped.

Where do I get a script? What dosage is the script for?

They emailed back "good morning, do you have a medical prescription?" What do I do? I'm nervous that they don't think they are allowed to send me the dutesteride.

But I can't find topical dutesteride on the website you gave. Can you give a link to actual topical dutesteride?

But where on this website is dutesteride?

I'm in the USA.

I didn't ignore anything. You gave multiple reasons. I said one reason sucked. I didn't comment on the other reasons because I had nothing to add on them. What is their website? I could not find it on google. I am trying to assess all my options, their costs, and estimated efficacy before deciding whether to take the plunge and go with the expensive Xyon. I also got to consider whether there is room in my budget for CosmeRNA. Using CosmeRNA and Xyon is one pretty penny.

You've been duped by marketing. Xyon could, just as easily, have upped the price per bottle and totally gotten ride of all consult fees. That is actually what anagenica does. Now, there are good reasons not to get Xyon. Maybe you aren't rich, and Xyon costs the most. Also there will never be large scale studies to prove Xyon causes less systemic effects. But a very bad reason not to get Xyon is how they break up the price between bottles and consult fees. You're taking a stand on principle without realizing the only principle here is marketing.

1. Whose topical dutesteride will work better? 2. Whose topical dutesteride is cheaper? 3. About how much are each? Minoxidil pills are covered by my insurance. So is finasteride pills, but they end my libido. Money isn't unlimited with me, as with some of you. So which topical finasteride is cheap? I'm already planning to pay a fortune for CosmeRNA.

1. This is the disadvantage of videos instead of writings. The speaker is vague, and might not mean exactly what he appears to say. He uses the word "combination," and then he throws in the kitchen sink. I don't think he really means you should take oral and topical minoxidil at the same time. I have never heard any doctor say to take both. 2. What is the best topical anti androgen?

I don't understand. 1. Is he saying to take oral and topical minoxidal at the same time? 2. Is he saying to take Dutesteride orally, topically, and through mesotherapy at the same time? 3. What are the anti-androgens he is recommending?

But you said Minoxidil with Trichoxidil gives better results than Minoxidil alone. So Trichoxidil should still be famous.

But why isn't Trichoxidil better known, if there is all that much evidence it works?

Do people take trichoxidil and minoxidal at the same time, or it is one or the other?

I micro needle anyway 1.5 mm three times a week. Some doctors think it grows hair. It is a bit painful. You don't really get used to the pain. I think the anagenica.com website says you can use both LipoDut .05% and DutMeso .01% because we simply don't know whether both might do more a bit more good than one alone. There isn't much data. I suspect DutMeso .01% does more than LipoDut .05%. It just seems logical there should be some payoff from the needle pain; it might penetrate deeper; it might also unfortunately go systemic more with more sex effects. All speculation.

https://anagenica.com is really bad at communicating. Most of my emails are ignored. I got from them "DutMeso .01%" https://anagenica.com/product/dutmeso-0-01/ 1. So do I use an electric micro-needler to poke 1 mm holes, and then apply 2 mL once a week? 2. The bottle has 60 mL. At 2 mL/week, it would last 30 weeks, but it says it is only good 3 month. You lose one month to shipping. So am I supposed to throw the bottle out after 8 weeks using only 16 mL (2 mL/week)? 3. It looks to me that they have a product where you don't microneedle LipoDut .05%. https://anagenica.com/product/lipodut-0-1/ What is better LipoDut .05%, or microneedling with DutMeso .01% ? 4. Should I use them both? It says you can. "This formulation can be used together with CB-03-01 or Dutasteride Mesotherapy." https://www.fueclinic.com/services/treatments/lipodut/ Thanks.

Can you give a link to mustang's thread? I can't find it. Thanks.

You want a good rationale. Doctors reject that approach. They think biological functions are too complicated for us to figure out rationales. Doctors just look at the data. The little data we have has shown keto helps a bit. We don't have much data. If it were ever researched more, the new data might say the opposite. This reminds me of the debates 10 years ago here over laser therapy. Back then, most doctors said lasers do nothing. They even said there is no way the laser can penetrate the scalp. Gradually over the next ten years, studies came out that say lasers work. Today, the majority of doctors think lasers work. By the way, in the US, 1% keto is over the counter. 2% is script. It is probably that way everywhere.