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Hair Loss Drugs Share your opinions and experiences regarding drugs like Propecia (finasteride), Minoxidil and others.

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Old 09-26-2012, 06:44 PM
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Good luck here, means: good luck not risking mammary glands enlargement, erectile dysfunction, headaches, permanent libido loss, etc...
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Old 09-26-2012, 07:02 PM
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gasto did you have a bad exeperience with propecia? if so how long have you been on the meds?
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Old 09-26-2012, 07:30 PM
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I went through it for 3 years. I did have some lower dosages at the end of the treatment and finally quited. Right now I am fine, apart from some occasional red knuckles I get every now and then.

I haven't had the serious side effects(like permanent libido loss), but when in treatment, my head seemed to have some electrical spikes in the back, where the cervical is. I read that this drug also interferes with the binding of Dihydrotestosterone to Allopregnanolone(the latter being responsible for the formation of myelin, the substance surrounding and insulating neurons). So as you can guess, 5 Alpha Reductase type I inhibition disrupts the normal functioning of the brain. I only experienced some electrical spikes, other people have reported foggy consciousness, and memory loss.

Dutasteride effects are even worse, because it also inhibits 5 Alpha Reductase type II

If you still decide to take this very dangerous drug, talk to a neurologist about what I have mentioned here beforehand.

Also consider the potential permanent side-effects:

http://onlinelibrary.wiley.com/doi/1...4CE6815.d03t01

http://www.ncbi.nlm.nih.gov/pubmed/21176115

Last edited by gasto; 09-26-2012 at 08:11 PM.
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Old 09-26-2012, 08:43 PM
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ive just recently started both propecia and rogaine foam, nothing really to report as of yet its to early, i know the drug has been out over 10 years i think, and only a few have side effects, from my research,i never heard of severe side effects with this drug, why would almost all ht docs say to get on meds to help keep what hair you have. if the side effects would make you seriously ill ?
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Old 09-28-2012, 09:56 AM
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They look at the data out there. Unfortunately, only statistical data that supports its usage is out there, mainly because of marketing reasons. I am sure that when publicly funded studies arise, the data will be less prone to bias.

I would like you to read this from nothing less than your beloved FDA:

Q4. What data are available on this safety issue?
A. The data that formed the basis for these labeling changes were based on two large, randomized controlled studies assessing the ability of 5-ARIs to reduce the rate of diagnosis of prostate cancer over a period of 7 years (Proscar) and 4 years (Avodart), respectively, in men at least 50 years of age. The Proscar trial evaluated the use of 5 mg doses of finasteride (Proscar) versus a placebo (sugar pill), and the Avodart trial evaluated the use of 0.5 mg doses of dutasteride (Avodart) versus a placebo, for the reduction of prostate cancer risk.
The trials demonstrated an overall reduction in prostate cancer diagnoses with finasteride and dutasteride treatment (see the Drug Safety Communication Data Summary for more information). This overall reduction was due to a decreased incidence of lower risk forms of prostate cancer. However, both the finasteride trial and the dutasteride trial showed an increased risk of high-grade prostate cancer.
It is important to note that neither trial evaluated 1 mg doses of finasteride (Propecia), used to treat male pattern hair loss.

Reference:



Prostate Cancer Prevention Trial (PCPT) - National Cancer Institute



As the following prominent institution proclaims, there must be more studies made to understand the causes of severe problems:

"
At the present time, the mechanism of interaction between the brain, 5 alpha-reductase metabolism, and hormones on sexual dysfunction is speculative and poorly understood. Clearly, this is a complicated issue, which overlaps with other disciplines in medicine such as Endocrinology, Urology, and Psychiatry. More research is needed to assess the actual incidence of side effects, to determine if there is a true causal relationship for persistent side effects, and, if so, to identify who may be at risk. We hope to participate in a multidisciplinary forum to further evaluate this topic.
"


Reference:

ISHRS Task Force on Finasteride Adverse Event Controversies


In other words, I would wait for more independent scientific studies.
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Old 09-28-2012, 11:17 AM
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thnks for the info.......
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Old 09-28-2012, 12:22 PM
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Bare in mind I am here for objective reasoning. If you are going to take the pill, you have done so at your own risk and in full knowledge of the potential risks. There is nothing worse than taking blind decisions.

Also take into consideration, that it is a life-long commitment. As soon as the ingestion of finasteride is stopped, the hair starts falling and all the previously gained hair is lost.
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Old 09-28-2012, 01:34 PM
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Fin is a half-measure imo. More permanent solutions should be sought.
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Old 09-28-2012, 02:25 PM
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I haven't found side effects of hair transplants as of yet. The only down turn is that the excellent hair restoration surgeons are expensive, but from my understanding, definitely worth.
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