Here's another interesting find:



The chart above (from the Gisleskog study of finasteride and dutasteride) measures finasteride levels (not DHT) in the blood over a 24 hour period after a single 5mg dose. Apparently blood levels of the drug peak rapidly 2 - 3 hours after taking a dose and then drop sharply the rest of the day. However, the other charts indicate that DHT remains fairly suppressed for several days after a single dose.

I think that's why some people elect to split their dosage into morning and evening doses, because they believe it helps keep serum finasteride levels higher throughout the day, but I'm not sure if that affects DHT suppression. If it does, it's probably to such a small degree that it may not be worth the added inconvenience.

i searched this and found this thread thanks for the good info

Bumping this thread up again! This thread should deserve more views.

PS: Has anyone tried dosing down on Finasteride?

I've been on 1 mg Propecia once every 2 days and so far I DO experience hair shed. HOWEVER, the time when I started skipping the dosage was also when I started using Rogaine foam.

Zenmunk, thanks for your excellent post. Very insightful and useful for people on the drug and for those who are planing to start. I think if we can seek comments/thoughts from medical experts/doctors in this field, that would be more interesting to see what their views are. Thanks again.

Nice work THANKS

Excellent thread, and one in which is very topical to my own situation right now.

I experienced some ED last year while on 1.25mg daily, so for the past few months I've trying 1.25mg on MWF.

However, having met Dr. Feriduni last week and discussing medication in great detail as well as other things, he felt it might be in my best interests to do something like 0.5mg daily, instead of 1.25mg three days a week.

His reasoning (and I'm paraphrasing slightly, but it's along these lines) was that the body prefers when there is a steady, consistent stream of going through. So instead of a slight zig zagging of hormones by going the MWF route, the body would have a nice flat steady balance if 0.5mg was taken daily. I'm going to finish out my current dose while I have the 5mg tablets, but I reckon I'll switch to 0.5mg daily then, once I've gotten my hands on the 1mg tablet.

__________________
2,000 FUE with Dr Bisanga - BHR Clinic, 22-23 August 2013

Current Regimen:
- 1.25mg Finasteride every MWF
- Rogaine Foam 5% every night - Only apply to crown
- Nizoral 2% 2 times p/week
- Alpecin C1 shampoo daily
- Multi Vit, Omegas, MSM, Saw Palmetto, Biotin

What is the overall consensus on this?

I take 1.25mg every other day. Is that what most others take as well or should I be going every day?

I see you started another thread on this but I thought it might be best to keep it on this one since it is very good.

Everyone will have their own reasoning as to how often they take the drug. Naturally the recommended is 1.25mg per day (well it's actually 1mg, but the 5mg tab is more popular and cheaper and therefore easier if split in four).

The majority of people that I have seen who are taking the drug every other day, are doing so because they didn't like how daily doses were going from a side effect point of view. Either that, or they are just beginning the drug and what to start on a smaller dose. Both make sense.

I started out taking 1.25mg every day for about 2 years. However, I noticed side effects, so I've now adjusted it to 1.25mg three days a week. The sides are not as intense now.

However, when I go to Dr Bisanga for my procedure in August, I'm getting a prescription for the 1mg tabs as I intend on switching my dose to 0.5mg per day. I feel that a steady, daily flow is slightly better than the up and down pattern that I discussed in my previous post.

The important thing is that you are taking Fin. If you can take 1.25mg per day without experiencing any side effects, then by all means take it every day. You will have the optimum level of protection against DHT.

All of the above is just my opinion however, but having spoken to several ht docs in person recently about it, I'm confident enough in it. It's essentially a case of you tailoring your own regimen to suit your body/needs.

__________________
2,000 FUE with Dr Bisanga - BHR Clinic, 22-23 August 2013

Current Regimen:
- 1.25mg Finasteride every MWF
- Rogaine Foam 5% every night - Only apply to crown
- Nizoral 2% 2 times p/week
- Alpecin C1 shampoo daily
- Multi Vit, Omegas, MSM, Saw Palmetto, Biotin

What a informative thread!

I've been taking 2.5mg MWF for 2 months now and haven't noticed anything bad. I've been thinking myself that it seems like a steady flow from 1.25mg a day would be better, but it's near impossible to get those pills in 4's and you end up with a bunch of crushed mess in the bottle and mg dosage becomes wishy washy.

I think the 1mg tabs would make life much easier. How much more is the cost? I'm paying $55 for 30 Finasteride 5mg pills.

__________________
2500 grafts + Acell/PRP progress with Dr.Cooley 4/12/13
http://www.hairrestorationnetwork.co...dr-cooley.html

No, it's not that hard to cut them into 4. Just buy a pill splitter dude.