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Hair Loss Drugs Share your opinions and experiences regarding drugs like Propecia (finasteride), Minoxidil and others.

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Old 02-09-2009, 11:43 AM
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If I was to use kirkland brand minoxidil v.s. rogaine would it work just as well??
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Old 02-09-2009, 12:04 PM
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Yes. I've been using it for years, with positive response.
They're chemically identical.
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Old 02-14-2009, 11:12 AM
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hey mmhce
do you say they are chemically identical from the label descriptions, or do you know of some cool study or lab that showed they really were identical?

btw east of eden one of my favorite movies.
"hey aron, how come you haven't asked me where I been"
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Old 03-05-2009, 08:47 PM
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The Liquid is Identical as the Patent ran out which is just one reason why they developed the FOAM (to keep that share of the market) Just like Dow lost there patent with R12 freon they pushed for the new R134a as that is their baby as well. Global warming, yeah right, politics baby!
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Old 03-06-2009, 02:05 AM
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Interesting rjnebbo. I had asked the question on another thread if there was any evidence (scientific) that the foam migrates through the epidermis and dermis with any increased speed or has a longer potency (longer half life) but I guess that isn't true?
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Old 03-08-2009, 06:52 AM
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I posted a reply to this on page 3 of this sub forum on Jan 3rd answering this question. It is a poster session abstract cited in the original rogaine foam paper.

THE JOURNAL OF INVESTIGATIVE DERMATOLOGY
ABSTRACTS A1
124:4 APRIL 2005
Uptake of minoxidil from a new foam formulation devoid of propylene glycol to hamster ear
hair follicles
R Stehle,1 G Ewing,1 J Rundegren2 and B Kohut2 1 Pharmaceutical Sciences, Pfizer, Inc,
Kalamazoo, MI and 2 Consumer Healthcare, Pfizer, Inc, Morris Plains, NJ
Post-marketing studies show that the present topical minoxidil formulations are considered oily and
in some cases there are reports of skin irritation. A major cause of the apparent inferior cosmetic
properties and adverse effects of the current formulations on the skin is the rather high content of
propylene glycol. Thus a more cosmetically acceptable minoxidil foam formulation, devoid of propylene
glycol was developed. In order to test the availability of minoxidil to hair follicles hamster ears
were treated with minoxidil 5% foam in comparison to the current minoxidil 5% solution (Rogaine?
Extra Strength), which served as a positive control. The foam was liquefied by gentle heating to 40C
and then 20 ??l was withdrawn with a positive displacement syringe and spread on the ventral ear
surfaces of a hamster, continuously and lightly anesthetized by controlled inhalation of isoflurane.
After 1 to 2 hours, the animal was sacrificed and the ears removed and carefully dissected to isolate
the sebaceous gland minoxidil content as an aqueous solution. Each sample was analyzed by HPLC
with electrochemical detection against minoxidil as an external standard. After one hour of minoxidil
treatment of the hamster ears the foam showed a sebaceous gland uptake of 5.9% of the total
minoxidil, while the positive control showed an uptake of 2.0% of the total minoxidil. After 2 hours
of treatment the uptake from the foam was 6.5% in one series of experiments and 4.1% in another
series of experiments, while the uptake from the positive control was 1.2% only. Thus the delivered
dose of minoxidil from the foam to the hamster ear sebaceous glands after one hour treatment was
about three times higher than for the minoxidil 5% solution. After two hours of treatment the minoxidil
delivery from the foam formulation increased to 3.4 to 5.4 higher than for the minoxidil 5% solution.
It is concluded that the new minoxidil 5% foam formulation is delivering minoxidil more
effectively to the sebaceous gland of the hamster ear than does the current minoxidil 5% solution.
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Old 03-08-2009, 08:02 AM
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This reminds me of the old addage: "There three sides to every story".

I'm contented with the generic Kirkland and I already use 15% minoxidil.

I've made my decision for surgical intervention.

I don't think switching to foam will do anything for me.

Others will have to give their own opinion.

BTW good investigation/post lanthanos
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Old 03-08-2009, 08:56 AM
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Poor old hamster!.......sort of like Reservoir Dogs but with Minoxidil.
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Old 03-08-2009, 12:35 PM
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sorry mmhce I don't get the joke in your post.

You do or you don't use 15% minoxidil?
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Old 03-08-2009, 01:45 PM
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Oh that wasn't a joke...at least I hope the joke is not on me, because I have used 15% minoxidil for a couple of years found here:

http://genhair.com/

Alternately you can use Dr. Lee's formula here:

http://www.minoxidil.com/index.html

The higher concentrations, are used on the crown and hairline.
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